Research Area:
molecular recognition and sensor;Signal amplification method;Microfluidic biological analysis
Target-responsive DNA hydrogel for nonenzymatic and visual detection of glucose
Gas-generating reactions for point-of-care testing
Lateral flow assay with pressure meter readout for rapid point-of-care detection of disease-associated protein
Microwell Array Method for Rapid Generation of Uniform Agarose Droplets and Beads for Single Molecule Analysis
Detection of T4 Polynucleotide Kinase via Allosteric Aptamer Probe Platform
Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin
Selection and identification of transferrin receptor-specific peptides as recognition probes for cancer cells
A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability
Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis
Isolation, Detection, and Antigen-Based Profiling of Circulating Tumor Cells Using a Size-Dictated Immunocapture Chip
Integrating Target-Responsive Hydrogel with Pressuremeter Readout Enables Simple, Sensitive, User-Friendly, Quantitative Point-of-Care Testing
A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods
Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis
Enrichment and single-cell analysis of circulating tumor cells
Design and synthesis of target-responsive hydrogel for portable visual quantitative detection of uranium with a microfluidic distance-based readout device
Target-responsive DNAzyme hydrogel for portable colorimetric detection of lanthanide(III) ions
Afi-chip: An equipment-free, low-cost, and universal binding ligand affinity evaluation platform
Surface-Enhanced Raman Scattering Active Plasmonic Nanoparticles with Ultrasmall Interior Nanogap for Multiplex Quantitative Detection and Cancer Cell Imaging
Evolution of DNA aptamers for malignant brain tumor gliosarcoma cell recognition and clinical tissue imaging
Enzyme-Encapsulated Liposome-Linked Immunosorbent Assay Enabling Sensitive Personal Glucose Meter Readout for Portable Detection of Disease Biomarkers
Integration of target responsive hydrogel with cascaded enzymatic reactions and microfluidic paper-based analytic devices (μPADs) for point-of-care testing (POCT)
Detection of DNA methyltransferase activity using allosteric molecular beacons
A pressure-based bioassay for the rapid, portable and quantitative detection of C-reactive protein
Distance-based microfluidic quantitative detection methods for point-of-care testing
Advance in phage display technology for bioanalysis
Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold
Recent Progress in Aptamer-Based Functional Probes for Bioanalysis and Biomedicine
DNA-Mediated Morphological Control of Silver Nanoparticles
Selection and Application of DNA Aptamer Against Oncogene Amplified in Breast Cancer 1
Translating Molecular Recognition into a Pressure Signal to enable Rapid, Sensitive, and Portable Biomedical Analysis
Simple and Rapid Functionalization of Gold Nanorods with Oligonucleotides Using an mPEG-SH/Tween 20-Assisted Approach
Stable DNA Nanomachine Based on Duplex-Triplex Transition for Ratiometric Imaging Instantaneous pH Changes in Living Cells
Evolution of DNA aptamers through in vitro metastatic-cell-based systematic evolution of ligands by exponential enrichment for metastatic cancer recognition and imaging
Target-responsive DNA hydrogel mediated stop-flow microfluidic paper-based analytic device for rapid, portable and visual detection of multiple targets
Design and synthesis of target-responsive aptamer-cross-linked hydrogel for visual quantitative detection of ochratoxin A
A label-free fluorescence strategy for sensitive detection of ATP based on the ligation-triggered super-sandwich
Target-responsive DNAzyme cross-linked hydrogel for visual quantitative detection of lead
Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing
Trifluoromethylated nucleic acid analogues capable of self-assembly through hydrophobic interactions
A cell-surface-anchored ratiometric fluorescent probe for extracellular pH sensing
Label-free fluorescence strategy for sensitive detection of adenosine triphosphate using a loop DNA probe with low background noise
In Vitro Selection of DNA Aptamers for Metastatic Breast Cancer Cell Recognition and Tissue Imaging
Monoclonal Surface Display SELEX for Simple, Rapid, Efficient, and Cost-Effective Aptamer Enrichment and Identification
Facile and Rapid Generation of Large-Scale Microcollagen Gel Array for Long-Term Single-Cell 3D Culture and Cell Proliferation Heterogeneity Analysis
In Vitro and in Vivo Studies on the Transport of PEGylated Silica Nanoparticles across the Blood-Brain Barrier
A highly parallel microfluidic droplet method enabling single-molecule counting for digital enzyme detection
A multifunctional nanomicelle for real-time targeted imaging and precise near-infrared cancer therapy
Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification
A diazirine-based photoaffinity probe for facile and efficient aptamer-protein covalent conjugation
A T7 exonuclease-assisted cyclic enzymatic amplification method coupled with rolling circle amplification: a dual-amplification strategy for sensitive and selective microRNA detection
Graphene oxide protected nucleic acid probes for bioanalysis and biomedicine
Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture
Engineering a cell-surface aptamer circuit for targeted and amplified photodynamic cancer therapy
An electrochemical sensor based on label-free functional allosteric molecular beacons for detection target DNA/miRNA
Target-responsive "sweet" hydrogel with glucometer readout for portable and quantitative detection of non-glucose targets
Stabilization of ssRNA on Graphene Oxide Surface: An Effective Way to Design Highly Robust RNA Probes
DNA micelle flares for intracellular mrna imaging and gene therapy
Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene
Backbone-modified molecular beacons for highly sensitive and selective detection of microRNAs based on duplex specific nuclease signal amplification
Cyclic enzymatic amplification method (CEAM) based on exonuclease III for highly sensitive bioanalysis
A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer-Protein Interactions
Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity
In vitro selection of highly efficient G-quadruplex-based DNAzymes
Single-molecule force spectroscopic studies on intra- and intermolecular interactions of G-quadruplex aptamer with target Shp2 protein
Mass Amplifying Probe for Sensitive Fluorescence Anisotropy Detection of Small Molecules in Complex Biological Samples
Single-molecule emulsion PCR in microfluidic droplets
Massively parallel single-molecule and single-cell emulsion reverse transcription polymerase chain reaction using agarose droplet microfluidics
Highly parallel single-molecule amplification approach based on agarose droplet polymerase chain reaction for efficient and cost-effective aptamer selection
Aptamer-incorporated hydrogels for visual detection, controlled drug release, and targeted cancer therapy
Highly sensitive and quantitative detection of rare pathogens through agarose droplet microfluidic emulsion PCR at the single-cell level
Backbone modification promotes peroxidase activity of G-quadruplex-based DNAzyme
Caged molecular beacons: controlling nucleic acid hybridization with light
DNA功能化金纳米及其应用
中国科学:化学,1674-7224 ,2015-11-20.纸芯片微流控技术的发展及应用
分析测试学报,1004-4957 ,2015-03-31.氧化石墨烯保护的核酸分子探针及其在生物分析中的应用
厦门大学学报(自然科学版),0438-0479 ,2014-09-28.