Design and synthesis of ortho-phthalaldehyde phosphoramidite for single-step, rapid, efficient and chemoselective coupling of DNA with proteins under physiological conditions

Integrated paper-based microfluidic devices for point-of-care testing

DNA aptamers from whole-cell SELEX as new diagnostic agents against glioblastoma multiforme cells

In Situ Pt Staining Method for Simple, Stable, and Sensitive Pressure-Based Bioassays

Highly Sensitive and Automated Surface Enhanced Raman Scattering-based Immunoassay for H5N1 Detection with Digital Microfluidics

Target-responsive DNA hydrogel for nonenzymatic and visual detection of glucose

Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography

Lateral flow assay with pressure meter readout for rapid point-of-care detection of disease-associated protein

Gas-generating reactions for point-of-care testing

Microwell Array Method for Rapid Generation of Uniform Agarose Droplets and Beads for Single Molecule Analysis

Detection of T4 Polynucleotide Kinase via Allosteric Aptamer Probe Platform

Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin

Selection and identification of transferrin receptor-specific peptides as recognition probes for cancer cells

A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability

Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis

Isolation, Detection, and Antigen-Based Profiling of Circulating Tumor Cells Using a Size-Dictated Immunocapture Chip

Integrating Target-Responsive Hydrogel with Pressuremeter Readout Enables Simple, Sensitive, User-Friendly, Quantitative Point-of-Care Testing

A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods

Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis

Enrichment and single-cell analysis of circulating tumor cells

Design and synthesis of target-responsive hydrogel for portable visual quantitative detection of uranium with a microfluidic distance-based readout device

Target-responsive DNAzyme hydrogel for portable colorimetric detection of lanthanide(III) ions

Afi-chip: An equipment-free, low-cost, and universal binding ligand affinity evaluation platform

Surface-Enhanced Raman Scattering Active Plasmonic Nanoparticles with Ultrasmall Interior Nanogap for Multiplex Quantitative Detection and Cancer Cell Imaging

Evolution of DNA aptamers for malignant brain tumor gliosarcoma cell recognition and clinical tissue imaging

Enzyme-Encapsulated Liposome-Linked Immunosorbent Assay Enabling Sensitive Personal Glucose Meter Readout for Portable Detection of Disease Biomarkers

Integration of target responsive hydrogel with cascaded enzymatic reactions and microfluidic paper-based analytic devices (μPADs) for point-of-care testing (POCT)

Detection of DNA methyltransferase activity using allosteric molecular beacons

Distance-based microfluidic quantitative detection methods for point-of-care testing

Advance in phage display technology for bioanalysis

Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold

Recent Progress in Aptamer-Based Functional Probes for Bioanalysis and Biomedicine

A pressure-based bioassay for the rapid, portable and quantitative detection of C-reactive protein

DNA-Mediated Morphological Control of Silver Nanoparticles

Selection and Application of DNA Aptamer Against Oncogene Amplified in Breast Cancer 1

Translating Molecular Recognition into a Pressure Signal to enable Rapid, Sensitive, and Portable Biomedical Analysis

Simple and Rapid Functionalization of Gold Nanorods with Oligonucleotides Using an mPEG-SH/Tween 20-Assisted Approach

Stable DNA Nanomachine Based on Duplex-Triplex Transition for Ratiometric Imaging Instantaneous pH Changes in Living Cells

Evolution of DNA aptamers through in vitro metastatic-cell-based systematic evolution of ligands by exponential enrichment for metastatic cancer recognition and imaging

Target-responsive DNA hydrogel mediated stop-flow microfluidic paper-based analytic device for rapid, portable and visual detection of multiple targets

Design and synthesis of target-responsive aptamer-cross-linked hydrogel for visual quantitative detection of ochratoxin A

A label-free fluorescence strategy for sensitive detection of ATP based on the ligation-triggered super-sandwich

Target-responsive DNAzyme cross-linked hydrogel for visual quantitative detection of lead

Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing

Trifluoromethylated nucleic acid analogues capable of self-assembly through hydrophobic interactions

A cell-surface-anchored ratiometric fluorescent probe for extracellular pH sensing

Label-free fluorescence strategy for sensitive detection of adenosine triphosphate using a loop DNA probe with low background noise

In Vitro Selection of DNA Aptamers for Metastatic Breast Cancer Cell Recognition and Tissue Imaging

Microfluidic approaches to rapid and efficient aptamer selection

Monoclonal Surface Display SELEX for Simple, Rapid, Efficient, and Cost-Effective Aptamer Enrichment and Identification

Facile and Rapid Generation of Large-Scale Microcollagen Gel Array for Long-Term Single-Cell 3D Culture and Cell Proliferation Heterogeneity Analysis

In Vitro and in Vivo Studies on the Transport of PEGylated Silica Nanoparticles across the Blood-Brain Barrier

A highly parallel microfluidic droplet method enabling single-molecule counting for digital enzyme detection

A T7 exonuclease-assisted cyclic enzymatic amplification method coupled with rolling circle amplification: a dual-amplification strategy for sensitive and selective microRNA detection

A multifunctional nanomicelle for real-time targeted imaging and precise near-infrared cancer therapy

Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

A diazirine-based photoaffinity probe for facile and efficient aptamer-protein covalent conjugation

Graphene oxide protected nucleic acid probes for bioanalysis and biomedicine

Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture

Engineering a cell-surface aptamer circuit for targeted and amplified photodynamic cancer therapy

An electrochemical sensor based on label-free functional allosteric molecular beacons for detection target DNA/miRNA

Target-responsive "sweet" hydrogel with glucometer readout for portable and quantitative detection of non-glucose targets

Stabilization of ssRNA on Graphene Oxide Surface: An Effective Way to Design Highly Robust RNA Probes

DNA micelle flares for intracellular mrna imaging and gene therapy

Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene

Backbone-modified molecular beacons for highly sensitive and selective detection of microRNAs based on duplex specific nuclease signal amplification

Cyclic enzymatic amplification method (CEAM) based on exonuclease III for highly sensitive bioanalysis

A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer-Protein Interactions

L -DNA molecular beacon: A safe, stable, and accurate intracellular nano-thermometer for temperature sensing in living cells

In vitro selection of highly efficient G-quadruplex-based DNAzymes

Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity

Identification, Characterization and Application of a G-Quadruplex Structured DNA Aptamer against Cancer Biomarker Protein Anterior Gradient Homolog 2

Single-molecule force spectroscopic studies on intra- and intermolecular interactions of G-quadruplex aptamer with target Shp2 protein

Mass Amplifying Probe for Sensitive Fluorescence Anisotropy Detection of Small Molecules in Complex Biological Samples

Single-molecule emulsion PCR in microfluidic droplets

Massively parallel single-molecule and single-cell emulsion reverse transcription polymerase chain reaction using agarose droplet microfluidics

Highly parallel single-molecule amplification approach based on agarose droplet polymerase chain reaction for efficient and cost-effective aptamer selection

Aptamer-incorporated hydrogels for visual detection, controlled drug release, and targeted cancer therapy

Highly sensitive and quantitative detection of rare pathogens through agarose droplet microfluidic emulsion PCR at the single-cell level

Backbone modification promotes peroxidase activity of G-quadruplex-based DNAzyme

Caged molecular beacons: controlling nucleic acid hybridization with light