Researcher's Profile

Research Area:

Chemical biology and medicinal chemistry

  • New 12,8-Eudesmanolides from Eutypella sp 1-15

    JOURNAL OF ANTIBIOTICS,0021-8820 ,2017-10.
    Wang, Yuezhou; Wang, Yue; Wu, An-an; Zhang, Lei; Hu, Zhiyu; Huang, Huiying; Xu, Qingyan; Deng, Xianming
    WOS:000411918400010   10.1038/ja.2017.89
    Included in : SCIE
  • Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

    CANCER CELL,1535-6108 ,2017-05-08.
    Zhang, Shihao; Chen, Qinghua; Liu, Qingxu; Li, Yuxi; Sun, Xiufeng; Hong, Lixin; Ji, Suyuan; Liu, Chengyan; Geng, Jing; Zhang, Weiji; Lu, Zhonglei; Yin, Zhen-Yu; Zeng, Yuanyuan; Lin, Kwang-Huei; Wu, Qiao; Li, Qiyuan; Nakayama, Keiko; Nakayama, Keiich I.; Deng, Xianming; Johnson, Randy L.; Zhu, Liang; Gao, Daming; Chen, Lanfen; Zhou, Dawang
    WOS:000400738600010   10.1016/j.ccell.2017.04.004
    Included in : SCIE
  • Nonomuraea ceibae sp nov., an actinobacterium isolated from Ceiba speciosa rhizosphere

    INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,1466-5026 ,2017-05.
    Wang, Fei; Shi, Jindi; Huang, Yaojian; Wu, Yingying; Deng, Xianming
    WOS:000403696100009   10.1099/ijsem.0.001782
    Included in : SCIE
  • Mycoepoxydiene suppresses HeLa cell growth by inhibiting glycolysis and the pentose phosphate pathway

    Applied Microbiology and Biotechnology,0175-7598 ,2017-02-21.
    Jin, Kehua(1,2,3); Li, Li(1,2); Sun, Xihuan(1,2); Xu, Qingyan(1,2); Song, Siyang(1,2); Shen, Yuemao(4); Deng, Xianming(1,2)
    WOS:000400069500021   EI:20170803382175   10.1007/s00253-017-8187-7
    Included in : SCIE、EI
  • Identification of compounds with anti-human cytomegalovirus activity that inhibit production of IE2 proteins

    ANTIVIRAL RESEARCH,0166-3542 ,2017-02.
    Beelontally, Rooksarr; Wilkie, Gavin S.; Lau, Betty; Goodmaker, Charles J.; Ho, Catherine M. K.; Swanson, Chad M.; Deng, Xianming; Wang, Jinhua; Gray, Nathanael S.; Davison, Andrew J.; Strang, Blair L.
    WOS:000393008400008   10.1016/j.antiviral.2016.12.006
    Included in : SCIE
  • Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors

    CANCER RESEARCH,0008-5472 ,2017-01-01.
    Jiang, Jie; Gui, Fu; He, Zhixiang; Li, Li; Li, Yunzhan; Li, Shunying; Wu, Xinrui; Deng, Zhou; Sun, Xihuan; Huang, Xiaoxing; Huang, Wei; Han, Shang; Zhang, Ting; Wang, Zheng; Jiao, Bo; Song, Siyang; Wang, Hongrui; Chen, Lanfen; Zhou, Dawang; Liu, Qiang; Ren, Ruibao; Zhang, Jianming; Deng, Xianming
    WOS:000393187900016   10.1158/0008-5472.CAN-16-1038
    Included in : SCIE
  • Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics

    Advanced Materials,0935-9648 ,2017.
    Liu, Zehua(1); Li, Yunzhan(2,3); Li, Wei(1); Xiao, Chen(2,3); Liu, Dongfei(1,8); Dong, Chao(2,3); Zhang, Ming(2,3); M?kil?, Ermei(4); Kemell, Marianna(5); Salonen, Jarno(4); Hirvonen, Jouni T.(1); Zhang, Hongbo(6,7); Zhou, Dawang(2,3); Deng, Xianming(2,3); Santos, Hélder A.(1,8)
    EI:20174204274704   10.1002/adma.201703393
    Included in : EI
  • Structure Determinants of Lagunamide A for Anticancer Activity and Its Molecular Mechanism of Mitochondrial Apoptosis

    MOLECULAR PHARMACEUTICS,1543-8384 ,2016-11.
    Huang, Xiaoxing; Huang, Wei; Li, Li; Sun, Xihuan; Song, Siyang; Xu, Qingyan; Zhang, Lianru; Wei, Bang-Guo; Deng, Xianming
    WOS:000387428300015   10.1021/acs.molpharmaceut.6b00564
    Included in : SCIE
  • Leveraging unique structural characteristics of WNK kinases to achieve therapeutic inhibition

    SCIENCE SIGNALING,1945-0877 ,2016-10-18.
    Zhang, Jinwei; Deng, Xianming; Kahle, Kristopher T.
    WOS:000387029300003   10.1126/scisignal.aaj2227
    Included in : SCIE
  • Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-delta/gamma Inhibitors

    ACS MEDICINAL CHEMISTRY LETTERS,1948-5875 ,2016-10.
    Ferguson, Fleur M.; Ni, Jing; Zhang, Tinghu; Tesar, Bethany; Sim, Taebo; Kim, Nam Doo; Deng, Xianming; Brown, Jennifer R.; Zhao, Jean J.; Gray, Nathanael S.
    WOS:000385689300009   10.1021/acsmedchemlett.6b00209
    Included in : SCIE
  • Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

    SCIENCE TRANSLATIONAL MEDICINE,1946-6234 ,2016-08-17.
    Fan, Fuqin; He, Zhixiang; Kong, Lu-Lu; Chen, Qinghua; Yuan, Quan; Zhang, Shihao; Ye, Jinjin; Liu, Hao; Sun, Xiufeng; Geng, Jing; Yuan, Lunzhi; Hong, Lixin; Xiao, Chen; Zhang, Weiji; Sun, Xihuan; Li, Yunzhan; Wang, Ping; Huang, Lihong; Wu, Xinrui; Ji, Zhiliang; Wu, Qiao; Xia, Ning-Shao; Gray, Nathanael S.; Chen, Lanfen; Yun, Cai-Hong; Deng, Xianming; Zhou, Dawang
    WOS:000384013700002   10.1126/scitranslmed.aaf2304
    Included in : SCIE
  • Direct Targeting of beta-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/beta-Catenin Signaling

    CELL REPORTS,2211-1247 ,2016-06-28.
    Hwang, So-Young; Deng, Xianming; Byun, Sanguine; Lee, Chan; Lee, Seung-Joo; Suh, Hyunsuk; Zhang, Jianming; Kang, Qiaofeng; Zhang, Ting; Westover, Kenneth D.; Mandinova, Anna; Lee, Sam W.
    WOS:000378950700004   10.1016/j.celrep.2016.05.071
    Included in : SCIE
  • Two New Ring A-Cleaved Lanostane-Type Triterpenoids and Four Known Steroids Isolated from Endophytic Fungus Glomerella sp. F00244

    Helvetica Chimica Acta,0018-019X ,2016.
    Guo, Kai(1,2,3); Fang, Huiqin(1,2); Gui, Fu(1,2); Wang, Yuezhou(1,2); Xu, Qinyan(1,2); Deng, Xianming(1,2)
    WOS:000383473800005   EI:20163202682330   10.1002/hlca.201600039
    Included in : SCIE、EI
  • Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,0027-8424 ,2015-12-29.
    Yin, Jie; Leavenworth, Jianmei W.; Li, Yang; Luo, Qi; Xie, Huafeng; Liu, Xinhua; Huang, Shan; Yan, Han; Fu, Zheng; Zhang, Liyun Y.; Zhang, Litao; Hao, Junwei; Wu, Xudong; Deng, Xianming; Roberts, Charles W. M.; Orkin, Stuart H.; Cantor, Harvey; Wang, Xi
    WOS:000367234700067   10.1073/pnas.1521740112
    Included in : SCIE
  • Cytochalasans and Sesquiterpenes from Eutypella scoparia 1-15

    NATURAL PRODUCT COMMUNICATIONS,1934-578X ,2015-12.
    Qi, Shuang; Wang, Yue; Zheng, Zhonghui; Xu, Qingyan; Deng, Xianming
    WOS:000367211300006  
    Included in : SCIE
  • Aspertetranones A-D, Putative Meroterpenoids from the Marine Algal-Associated Fungus Aspergillus sp ZL0-1b14

    JOURNAL OF NATURAL PRODUCTS,0163-3864 ,2015-10.
    Wang, Yuezhou; Qi, Shuang; Zhan, Ying; Zhang, Nanwen; Wu, An-an; Gui, Fu; Guo, Kai; Yang, Yanru; Cao, Shugeng; Hu, Zhiyu; Zheng, Zhonghui; Song, Siyang; Xu, Qingyan; Shen, Yuemao; Deng, Xianming
    WOS:000363995800013   10.1021/acs.jnatprod.5b00487
    Included in : SCIE
  • Kribbella mirabilis sp nov., isolated from rhizosphere soil of a herbaceous plant, Mirabilis jalapa L.

    INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,1466-5026 ,2015-09.
    Li, Dan; Song, Jiaojiao; Huang, Yaojian; Song, Siyang; Wu, Yingying; Deng, Xianming
    WOS:000364108400056   10.1099/ijsem.0.000393
    Included in : SCIE
  • The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma

    GUT,0017-5749 ,2015-09.
    Rovida, Elisabetta; Di Maira, Giovanni; Tusa, Ignazia; Cannito, Stefania; Paternostro, Claudia; Navari, Nadia; Vivoli, Elisa; Deng, Xianming; Gray, Nathanael S.; Esparis-Ogando, Azucena; David, Ezio; Pandiella, Atanasio; Dello Sbarba, Persio; Parola, Maurizio; Marra, Fabio
    WOS:000360389800015   10.1136/gutjnl-2014-306761
    Included in : SCIE
  • Kibdelosporangium lantanae sp nov., isolated from the rhizosphere soil of an ornamental plant, Lantana camara L.

    INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY,1466-5026 ,2015-08.
    Li, Dan; Huang, Yaojian; Song, Siyang; Xue, Ci; Wu, Yingying; Deng, Xianming
    WOS:000362384800037   10.1099/ijs.0.000302
    Included in : SCIE
  • Four New Cycloheximide Derivatives from Streptomyces sp h-119

    RECORDS OF NATURAL PRODUCTS,1307-6167 ,2015.
    Yang, Dou; Xu, Qing Yan; Deng, Xian Ming; Song, Si Yang; Hu, Zhi Yu; Zheng, Zhong Hui
    WOS:000361529300010  
    Included in : SCIE
  • Impeded Nedd4-1-Mediated Ras Degradation Underlies Ras-Driven Tumorigenesis

    CELL REPORTS,2211-1247 ,2014-05.
    Zeng, Taoling; Wang, Qun; Fu, Jieying; Lin, Qi; Bi, Jing; Ding, Weichao; Qiao, Yikai; Zhang, Sheng; Zhao, Wenxiu; Lin, Huayue; Wang, Meilin; Lu, Binfeng; Deng, Xianming; Zhou, Dawang; Yin, Zhenyu; Wang, Hong-Rui
    WOS:000335560900027   10.1016/j.celrep.2014.03.045
    Included in : SCIE
  • Leucine-rich repeat kinase 2 inhibitors: a patent review (2006-2011)

    EXPERT OPINION ON THERAPEUTIC PATENTS,1354-3776 ,2012-12.
    Deng, Xianming; Choi, Hwan Geun; Buhrlage, Sara J.; Gray, Nathanael S.
    WOS:000311420400003   10.1517/13543776.2012.729041
    Included in : SCIE
  • Pyrazolopyridines as inhibitors of the kinase LRRK2: a patent evaluation (WO2011141756)

    EXPERT OPINION ON THERAPEUTIC PATENTS,1354-3776 ,2012-06.
    Deng, Xianming; Gray, Nathanael S.
    WOS:000305245000008   10.1517/13543776.2012.691968
    Included in : SCIE
  • Hippo pathway in intestinal homeostasis and tumorigenesis

    PROTEIN & CELL,1674-800X ,2012-04.
    Chen, Lanfen; Qin, Funiu; Deng, Xianming; Avruch, Joseph; Zhou, Dawang
    WOS:000310527600008   10.1007/s13238-012-2913-9
    Included in : SCIE
  • 福建省药理学学科发展报告

    海峡科学,1673-8683 ,2016-01-15.
    许建华;贾力;金鑫;邓贤明;刁勇;黄枚;倪峰