Researcher's Profile

Research Area:

Chemical biology and medicinal chemistry

  • Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

    CANCER CELL,1535-6108 ,2017-05-08.
    Zhang, Shihao; Chen, Qinghua; Liu, Qingxu; Li, Yuxi; Sun, Xiufeng; Hong, Lixin; Ji, Suyuan; Liu, Chengyan; Geng, Jing; Zhang, Weiji; Lu, Zhonglei; Yin, Zhen-Yu; Zeng, Yuanyuan; Lin, Kwang-Huei; Wu, Qiao; Li, Qiyuan; Nakayama, Keiko; Nakayama, Keiich I.; Deng, Xianming; Johnson, Randy L.; Zhu, Liang; Gao, Daming; Chen, Lanfen; Zhou, Dawang
    WOS:000400738600010   10.1016/j.ccell.2017.04.004
    Included in : SCIE
  • Leveraging unique structural characteristics of WNK kinases to achieve therapeutic inhibition

    SCIENCE SIGNALING,1945-0877 ,2016-10-18.
    Zhang, Jinwei; Deng, Xianming; Kahle, Kristopher T.
    WOS:000387029300003   10.1126/scisignal.aaj2227
    Included in : SCIE
  • Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

    SCIENCE TRANSLATIONAL MEDICINE,1946-6234 ,2016-08-17.
    Fan, Fuqin; He, Zhixiang; Kong, Lu-Lu; Chen, Qinghua; Yuan, Quan; Zhang, Shihao; Ye, Jinjin; Liu, Hao; Sun, Xiufeng; Geng, Jing; Yuan, Lunzhi; Hong, Lixin; Xiao, Chen; Zhang, Weiji; Sun, Xihuan; Li, Yunzhan; Wang, Ping; Huang, Lihong; Wu, Xinrui; Ji, Zhiliang; Wu, Qiao; Xia, Ning-Shao; Gray, Nathanael S.; Chen, Lanfen; Yun, Cai-Hong; Deng, Xianming; Zhou, Dawang
    WOS:000384013700002   10.1126/scitranslmed.aaf2304
    Included in : SCIE
  • Direct Targeting of beta-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/beta-Catenin Signaling

    CELL REPORTS,2211-1247 ,2016-06-28.
    Hwang, So-Young; Deng, Xianming; Byun, Sanguine; Lee, Chan; Lee, Seung-Joo; Suh, Hyunsuk; Zhang, Jianming; Kang, Qiaofeng; Zhang, Ting; Westover, Kenneth D.; Mandinova, Anna; Lee, Sam W.
    WOS:000378950700004   10.1016/j.celrep.2016.05.071
    Included in : SCIE
  • Impeded Nedd4-1-Mediated Ras Degradation Underlies Ras-Driven Tumorigenesis

    CELL REPORTS,2211-1247 ,2014-05.
    Zeng, Taoling; Wang, Qun; Fu, Jieying; Lin, Qi; Bi, Jing; Ding, Weichao; Qiao, Yikai; Zhang, Sheng; Zhao, Wenxiu; Lin, Huayue; Wang, Meilin; Lu, Binfeng; Deng, Xianming; Zhou, Dawang; Yin, Zhenyu; Wang, Hong-Rui
    WOS:000335560900027   10.1016/j.celrep.2014.03.045
    Included in : SCIE
  • Hippo pathway in intestinal homeostasis and tumorigenesis

    PROTEIN & CELL,1674-800X ,2012-04.
    Chen, Lanfen; Qin, Funiu; Deng, Xianming; Avruch, Joseph; Zhou, Dawang
    WOS:000310527600008   10.1007/s13238-012-2913-9
    Included in : SCIE
  • 福建省药理学学科发展报告

    海峡科学,1673-8683 ,2016-01-15.
    许建华;贾力;金鑫;邓贤明;刁勇;黄枚;倪峰