Researcher's Profile

Research Area:

Chemical biology and medicinal chemistry

  • Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity

    NATURE COMMUNICATIONS,2041-1723 ,2018-06-29.
    He, HB; Jiang, H; Chen, Y; Ye, J; Wang, AL; Wang, C; Liu, QS; Liang, GL; Deng, XM; Jiang, W; Zhou, RB
    WOS:000436791400011   10.1038/s41467-018-04947-6
    Included in : SCIE
  • Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities

    JOURNAL OF MEDICINAL CHEMISTRY,0022-2623 ,2018-06-28.
    Huang, W; Sun, XH; Li, YZ; He, ZX; Li, L; Deng, Z; Huang, XX; Han, S; Zhang, T; Zhong, JJ; Wang, Z; Xu, QY; Zhang, JM; Deng, XM
    WOS:000437811200026   10.1021/acs.jmedchem.8b00753
    Included in : SCIE
  • ERK5 is activated by oncogenic BRAF and promotes melanoma growth

    ONCOGENE,0950-9232 ,2018-05.
    Tusa, I; Gagliardi, S; Tubita, A; Pandolfi, S; Urso, C; Borgognoni, L; Wang, JH; Deng, XM; Gray, NS; Stecca, B; Rovida, E
    WOS:000431873400001   10.1038/s41388-018-0164-9
    Included in : SCIE
  • Tranilast directly targets NLRP3 to treat inflammasome-driven diseases

    EMBO MOLECULAR MEDICINE,1757-4676 ,2018-04.
    Huang, Yi; Jiang, Hua; Chen, Yun; Wang, Xiaqiong; Yang, Yanqing; Tao, Jinhui; Deng, Xianming; Liang, Gaolin; Zhang, Huafeng; Jiang, Wei; Zhou, Rongbin
    WOS:000429322500010   10.15252/emmm.201708689
    Included in : SCIE