夏宁邵 (NingShao Xia)
生命科学学院
ResearcherID:G-4647-2010
2023年当选中国工程院院士。 入选中国医学科学院学部委员、国家杰出青年科学基金、教育部“长江学者奖励计划”特岗学者、国家特支计划科技创新领军人才、全国先进工作者、全国杰出专业技术人才、国家百千万人才工程。以第一完成人获国家技术发明二等奖、国家科技进步二等奖、全国创新争先奖、中国专利金奖、福建省科技重大贡献奖、厦门市科技重大贡献奖、求是杰出科技成就集体奖、转化医学杰出贡献奖。
已发表成果:
WOK 论文 557 篇;中文核心 176 篇;其它论文 55 篇;专利发明 57 个;
                                    
Engineering for an HPV 9-valent vaccine candidate using genomic constitutive over-expression and low lipopolysaccharide levels in Escherichia coli cells
                                    
                                
                                    
Transferable, easy-to-use and room-temperature-storable PCR mixes for microfluidic molecular diagnostics
                                    
                                
                                    
Antibody Generation and Immunogenicity Analysis of EBV gp42 N-Terminal Region
                                    
                                
                                    
Nanospheres from coordination polymers of Ag+ with a highly hydrophilic thiol ligand formed in situ from dynamic covalent binding and a hydrophobic thiol
                                    
                                
                                    
BRD4 inhibition boosts the therapeutic effects of epidermal growth factor receptor-targeted chimeric antigen receptor T cells in glioblastoma
                                    
                                
                                    
Capsid destabilization and epitope alterations of human papillomavirus 18 in the presence of thimerosal
                                    
                                
                                    
Rapid PCR powered by microfluidics: A quick review under the background of COVID-19 pandemic
                                    
                                
                                    
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
                                    
                                
                                    
Development of A Neonatal Mouse Model for Coxsackievirus B1 Antiviral Evaluation
                                    
                                
                                    
Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies
                                    
                                
                                    
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo
                                    
                                
                                    
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters
                                    
                                
                                    
Asymptomatic and Symptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in Close Contacts of Coronavirus Disease 2019 (COVID-19) Patients: A Seroepidemiological Study
                                    
                                
                                    
Naturally acquired HPV antibodies against subsequent homotypic infection: A large-scale prospective cohort study
                                    
                                
                                    
Rabbit Monoclonal Antibody Specifically Recognizing a Linear Epitope in the RBD of SARS-CoV-2 Spike Protein
                                    
                                
                                    
Elimination of human cytomegalovirus DNA degradation in urine
                                    
                                
                                    
Sporadic hand, foot, and mouth disease cases associated with non-C4 enterovirus 71 strains in Xiamen, China, from 2009 to 2018
                                    
                                
                                    
Accurate nucleic acid quantification in a single sample tube without the need for calibration
                                    
                                
                                    
Carbohydrate-containing nanoparticles as vaccine adjuvants
                                    
                                
                                    
Comparison of detection strategies for screening and confirming congenital cytomegalovirus infection in newborns in a highly seroprevalent population: a mother-child cohort study
                                    
                                
                                    
Lost Small Envelope Protein Expression from Naturally Occurring PreS1 Deletion Mutants of Hepatitis B Virus Is Often Accompanied by Increased HBx and Core Protein Expression as Well as Genome Replication
                                    
                                
                                    
Multimodal investigation of rat hepatitis E virus antigenicity: Implications for infection, diagnostics, and vaccine efficacy
                                    
                                
                                    
Establishment of a rapid ELISPOT assay for influenza virus titration and neutralizing antibody detection
                                    
                                
                                    
A Novel Clustering Method Using Variational Autoencoder with Reliable Sample Decision and Balanced K-Means++ for Single-particle Cryo-EM Images
                                    
                                
                                    
SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA
                                    
                                
                                    
Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding
                                    
                                
                                    
Role of Small Envelope Protein in Sustaining the Intracellular and Extracellular Levels of Hepatitis B Virus Large and Middle Envelope Proteins
                                    
                                
                                    
Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster
                                    
                                
                                    
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating
                                    
                                
                                    
The prevalence of antibodies to SARS-CoV-2 among blood donors in China
                                    
                                
                                    
Replication, pathogenicity, and transmission of SARS-CoV-2 in minks
                                    
                                
                                    
Naturally occurring 5' preS1 deletions markedly enhance replication and infectivity of HBV genotype B and genotype C
                                    
                                
                                    
Several FDA-Approved Drugs Effectively Inhibit SARS-CoV-2 Infection in vitro
                                    
                                
                                    
Adefovir dipivoxil efficiently inhibits the proliferation of pseudorabies virus in vitro and in vivo
                                    
                                
                                    
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors
                                    
                                
                                    
Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection
                                    
                                
                                    
Inflammation-related adverse reactions following vaccination potentially indicate a stronger immune response
                                    
                                
                                    
SARS-CoV-2 infection and disease outcomes in non-human primate models: advances and implications
                                    
                                
                                    
Machine Learning for Structure Determination in Single-Particle Cryo-Electron Microscopy: A Systematic Review
                                    
                                
                                    
A SCID mouse-human lung xenograft model of SARS-CoV-2 infection
                                    
                                
水痘-带状疱疹病毒ORF43蛋白的单克隆抗体制备及初步研究
病毒学报,1000-8721,2021-08-17.厦门市健康人群肠道病毒D68型血清流行病学调查
病毒学报,1000-8721,2021-07-23.新冠疫苗点亮希望之光
中国科学基金,1000-8217,2021-04-25.人乳头瘤病毒疫苗的研究进展
厦门大学学报(自然科学版),0438-0479,2021-03-28.以现实需求为导向搞科研育人才
光明日报,,2021-08-04.