夏宁邵 (NingShao Xia)
生命科学学院
ResearcherID:G-4647-2010
2023年当选中国工程院院士。 入选中国医学科学院学部委员、国家杰出青年科学基金、教育部“长江学者奖励计划”特岗学者、国家特支计划科技创新领军人才、全国先进工作者、全国杰出专业技术人才、国家百千万人才工程。以第一完成人获国家技术发明二等奖、国家科技进步二等奖、全国创新争先奖、中国专利金奖、福建省科技重大贡献奖、厦门市科技重大贡献奖、求是杰出科技成就集体奖、转化医学杰出贡献奖。
已发表成果:
WOK 论文 557 篇;中文核心 176 篇;其它论文 55 篇;专利发明 57 个;
                                    
Profile of clinical characteristics and serologic markers of sporadic hepatitis E in a community cohort study
                                    
                                
                                    
Safety of hepatitis E vaccination for pregnancy: a post-hoc analysis of a randomized, double-blind, controlled phase 3 clinical trial
                                    
                                
                                    
Molecular engineering tools for the development of vaccines against infectious diseases: current status and future directions
                                    
                                
                                    
In-depth review of delivery carriers associated with vaccine adjuvants: current status and future perspectives
                                    
                                
                                    
Neutralizing antibodies against EBV gp42 show potent <i>in vivo</i> protection and define novel epitopes
                                    
                                
                                    
System Design and Clinical Validation of Intelligent Nucleic Acid POCT for Ultra-High Sensitivity SARS-CoV-2 Detection within 30 Min
                                    
                                
                                    
Redeveloping antigen detection kits for the diagnosis of rat hepatitis E virus
                                    
                                
                                    
Safety and efficacy of the intranasal spray SARS-CoV-2 vaccine dNS1-RBD: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
                                    
                                
                                    
MHC class II regulation of CD8+T cell tolerance and implications in autoimmunity and cancer immunotherapy
                                    
                                
                                    
Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection
                                    
                                
                                    
Anti-BNLF2b Screening for Nasopharyngeal Cancer
                                    
                                
                                    
Head-to-head immunogenicity comparison of an<i> Escherichia</i> coli-produced 9-valent human papillomavirus vaccine and Gardasil 9 in women aged 18-26 years in China: a randomised blinded clinical trial
                                    
                                
                                    
The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors
                                    
                                
                                    
Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant
                                    
                                
                                    
The epidemiology of varicella and effectiveness of varicella vaccine in Ganyu, China: a long-term community surveillance study
                                    
                                
                                    
Reconsideration of Maternal Serological Testing for Predicting Congenital CMV Infection
                                    
                                
                                    
All-in-one microfluidic chip for 30-min quantitative point-of-care-testing of nucleic acids
                                    
                                
                                    
Butyrate Protects against SARS-CoV-2-Induced Tissue Damage in Golden Hamsters
                                    
                                
                                    
Anti-Epstein-Barr Virus BNLF2b for Mass Screening for Nasopharyngeal Cancer
                                    
                                
                                    
Evolving spike mutations in SARS-CoV-2 Omicron variants facilitate evasion from breakthrough infection-acquired antibodies
                                    
                                
                                    
Nanoparticle-based multivalent human antibodies offer potent and broad neutralization against Omicron sublineages
                                    
                                
                                    
Targeting herpesvirus entry complex and fusogen glycoproteins with prophylactic and therapeutic agents
                                    
                                
                                    
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
                                    
                                
                                    
Risedronate-Functionalized Manganese-Calcium Phosphate Nanoparticles: A Potent Adjuvant for Subunit Vaccines and Cancer Immunotherapy
                                    
                                
                                    
Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters
                                    
                                
                                    
Case Report: Chronic hepatitis E virus Infection in an individual without evidence for immune deficiency
                                    
                                
                                    
Structure and proposed DNA delivery mechanism of a marine roseophage
                                    
                                
                                    
Precision and correlation of ED50 and endpoint titer method in measuring HPV vaccine immunogenicity
                                    
                                
                                    
Design of Multicomponent Peptide Fibrils with Ordered and Programmable Compositional Patterns
                                    
                                
                                    
Design of Multicomponent Peptide Fibrils with Ordered and Programmable Compositional Patterns
                                    
                                
                                    
Combination therapy of therapeutic antibody and vaccine or entecavir in HBV carrier mice
                                    
                                
                                    
Hepatitis B Core Antibody Level: A Surrogate Marker for Host Antiviral Immunity in Chronic Hepatitis B Virus Infections
                                    
                                
                                    
Safety and immunogenicity of a skin- and neuro-attenuated live vaccine for varicella: a randomized, double-blind, controlled, dose-escalation and age de-escalation phase 1 clinical trial
                                    
                                
                                    
Ultra-fast, sensitive and low-cost real-time PCR system for nucleic acid detection
                                    
                                
                                    
Safety and immunogenicity of an<i> Escherichia</i> coli-produced 9-valent human papillomavirus L1 virus-like particle vaccine (types 6/11/16/18/31/33/45/52/58) in healthy adults: an open-label, dose-escalation phase 1 clinical trial
                                    
                                
                                    
Abnormally primed CD8 T cells: The Achilles' heel of CHB
                                    
                                
                                    
A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19
                                    
                                
                                    
Transcriptomics confirm the establishment of a liver-immune dual-humanized mouse model after transplantation of a single type of human bone marrow mesenchymal stem cell
                                    
                                
                                    
Progress in immunotherapy
                                    
                                
                                    
Ultrafast Microfluidic PCR Thermocycler for Nucleic Acid Amplification
                                    
                                
                                    
Bacterial-Artificial-Chromosome-Based Genome Editing Methods and the Applications in Herpesvirus Research
                                    
                                
                                    
All-in-One Microfluidic Chip for the Point-of-Care-Testing of Nucleic Acids: Combining a Dynamic-Seal Microvalve, Ultrasound-Assisted Reaction Chamber, and Slice Amplification with a Fluorescence Detection System
                                    
                                
                                    
Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for <i>Escherichia coli</i>-based vaccine design
                                    
                                
                                    
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16
                                    
                                
                                    
A Heterologous Challenge Rescues the Attenuated Immunogenicity of SARS-CoV-2 Omicron BA.1 Variant in Syrian Hamster Model
                                    
                                
                                    
An Automated TW3-RUS Bone Age Assessment Method with Ordinal Regression-Based Determination of Skeletal Maturity
                                    
                                
                                    
Antiviral Nanobiologic Therapy Remodulates Innate Immune Responses to Highly Pathogenic Coronavirus
                                    
                                
                                    
PointDE: Protein Docking Evaluation Using 3D Point Cloud Neural Network
                                    
                                
                                    
Immunogenicity and safety of an<i> Escherichia</i> coli-produced human papillomavirus (types 6/11/16/18/31/33/45/52/58) L1 virus-like-particle vaccine: a phase 2 double-blind, randomized, controlled trial
                                    
                                
新型抗体标志物P85-Ab提升鼻咽癌筛查效能
科学通报,0023-074X,2023-12-28.新冠RNA疫苗研究进展
病毒学报,1000-8721,2023-11-21.新冠RNA疫苗研究进展
病毒学报,1000-8721,2023-11-21.自组装颗粒化新冠疫苗研究进展
病毒学报,1000-8721,2023-11-21.HEV与细胞结合的氨基酸位点分析
中国生物工程杂志,1671-8135,2023-07-25.水痘带状疱疹病毒ORF41的单克隆抗体制备及其初步研究
中国免疫学杂志,1000-484X,2023-05-10.RSV疫苗取得突破进展
中国科学基金,1000-8217,2023-04-25.中国预防性人乳头瘤病毒疫苗研制及应用
中华疾病控制杂志,1674-3679,2023-03-10.新型抗体标志物P85-Ab提升鼻咽癌筛查效能
科学通报,,2023-12-28.基于大肠杆菌表达系统的人乳头瘤病毒疫苗研发进展
中国食品药品监管,1673-5390,2023-12-15.充分发挥疫苗创新优势 将厦门发展成疫苗创新名城
厦门科技,1007-1563,2023-10-28.