已发表成果:
WOK 论文 80 篇;中文核心 3 篇;其它论文 7 篇;专利发明 4 个;
Discovery of 4-((3,4-dichlorophenyl)amino)-2-methylquinolin-6-ol derivatives as EGFR and HDAC dual inhibitors
Design, synthesis, and biological evaluation of novel 4,4′-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer
Discovery of new DHA ethanolamine derivatives as potential anti-inflammatory agents targeting Nur77
Discovery of 5-(Pyrimidin-2-ylamino)-1<i>H</i>-indole-2-carboxamide Derivatives as Nur77 Modulators with Selective and Potent Activity Against Triple-Negative Breast Cancer
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77
Screening of small molecule compounds targeting hnRNPA2 protein
The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma
Identification and characterization of 7-azaindole derivatives as inhibitors of the SARS-CoV-2 spike-hACE2 protein interaction
Inhibition of Nur77 expression and translocation by compound B6 reduces ER stress and alleviates cigarette smoke-induced inflammation and injury in bronchial epithelial cells
Discovery of bipyridine amide derivatives targeting pRXR?-PLK1 interaction for anticancer therapy
The synthesis of PROTAC molecule and new target KAT6A identification of CDK9 inhibitor iCDK9
Lipidome remodeling activities of DPA-EA in palmitic acid-stimulated HepG2 cells and the <i>in vivo</i> anti-obesity effect of the DPA-EA and DHA-EA mixture prepared from algae oil
Identification of potential ATP-competitive cyclin-dependent kinase 1 inhibitors: De novo drug generation, molecular docking, and molecular dynamics simulation
Approved Small-Molecule ATP-Competitive Kinases Drugs Containing Indole/Azaindole/Oxindole Scaffolds: R&D and Binding Patterns Profiling