已发表成果:
WOK 论文 117 篇;中文核心 28 篇;其它论文 3 篇;专利发明 8 个;
A screening study on the detection strain of Coxsackievirus A6: the key to evaluating neutralizing antibodies in vaccines
Immunogenicity and safety of an<i> ORF7</i>-deficient skin- attenuated and neuro-attenuated live vaccine for varicella: a randomised, double-blind, controlled, phase 2atrial
Serological and Molecular Detection of Citrus Tristeza Virus: A Review
Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels
Construction and characterization of an infectious cDNA clone of human rhinovirus A89
Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
Cytomegalovirus-vectored COVID-19 vaccines elicit neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.2) in mice
A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection
Evolving spike mutations in SARS-CoV-2 Omicron variants facilitate evasion from breakthrough infection-acquired antibodies
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters
Safety and immunogenicity of a skin- and neuro-attenuated live vaccine for varicella: a randomized, double-blind, controlled, dose-escalation and age de-escalation phase 1 clinical trial
Rationally designed synthetic vectors for therapeutic nucleic acid delivery against human cytomegalovirus infection
A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19
Transcriptomics confirm the establishment of a liver-immune dual-humanized mouse model after transplantation of a single type of human bone marrow mesenchymal stem cell
Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for <i>Escherichia coli</i>-based vaccine design
Current Methods for the Detection of Antibodies of Varicella-Zoster Virus: A Review
A Heterologous Challenge Rescues the Attenuated Immunogenicity of SARS-CoV-2 Omicron BA.1 Variant in Syrian Hamster Model
Antiviral Nanobiologic Therapy Remodulates Innate Immune Responses to Highly Pathogenic Coronavirus
Nasal irrigation efficiently attenuates SARS-CoV-2 Omicron infection, transmission and lung injury in the Syrian hamster model
Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine
The duration and breadth of antibody responses to 3-dose of inactivated COVID-19 vaccinations in healthy blood donors: An observational study
MOLECULAR BASIS OF HEPATIC DIFFERENTIATION OF HUMAN BONE MARROW MESENCHYMAL STEM CELL IN VIVO
Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice
Infection, pathology and interferon treatment of the SARS-CoV-2 Omicron BA.1 variant in juvenile, adult and aged Syrian hamsters
Discovery and Optimization of Quinoline Analogues as Novel Potent Antivirals against Enterovirus D68
Development of a rapid neutralization testing system for Rhinovirus C15 based on the enzyme-linked immunospot assay
Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2
Baculovirus Display of Varicella-Zoster Virus Glycoprotein E Induces Robust Humoral and Cellular Immune Responses in Mice
Molecular basis of hepatic differentiation of human bone marrow mesenchymal stem cell in vivo
Development of a rapid neutralization assay for the detection of neutralizing antibodies against coxsackievirus B1
PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron
Rational Design of a Skin- and Neuro-Attenuated Live Varicella Vaccine: A Review and Future Perspectives
Cross-species tropism and antigenic landscapes of SARS-CoV-2 variants
Female sex hormone, progesterone, ameliorates the severity of SARS-CoV-2-caused pneumonia in the Syrian hamster model
Development of a skin- and neuro-attenuated live vaccine for varicella
Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19
Dexamethasone ameliorates severe pneumonia but slightly enhances viral replication in the lungs of SARS-CoV-2-infected Syrian hamsters
A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2
Evaluation of the cross-neutralization activities elicited by Coxsackievirus A10 vaccine strains
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters
Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating
The prevalence of antibodies to SARS-CoV-2 among blood donors in China
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors
SARS-CoV-2 infection and disease outcomes in non-human primate models: advances and implications
A SCID mouse-human lung xenograft model of SARS-CoV-2 infection
Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids
DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes
Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay
Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16
A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice
Animal models for emerging coronavirus: progress and new insights
HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation
A potential therapeutic neutralization monoclonal antibody specifically against multi-coxsackievirus A16 strains challenge
HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation
Agonist c-Met monoclonal antibody augments the proliferation of hiPSC-derived hepatocyte-like cells and improves cell transplantation therapy for liver failure in mice
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10
A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells
Robust in vitro assay for analyzing the neutralization activity of serum specimens against hepatitis B virus
Ferritin nanocage-based antigen delivery nanoplatforms: Epitope engineering for peptide vaccine design
Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Development of an efficient neutralization assay for Coxsackievirus A10
Agonist c-Met Monoclonal Antibody Augments the Proliferation of hiPSC-derived Hepatocyte-Like Cells and Improves Cell Transplantation Therapy for Liver Failure in Mice
HBV Infection-Induced Liver Cirrhosis Development in Dual-Humanized Mice with Human Bone Mesenchymal Stem Cell Transplantation
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10
Optimized HepaRG is a suitable cell source to generate the human liver chimeric mouse model for the chronic hepatitis B virus infection
ER stress regulating protein phosphatase 2A-B56 gamma, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes
A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus Infection
Oncolytic activity of a coxsackievirus B3 strain in human endometrial cancer cell lines
Serological survey of neutralizing antibodies to eight major enteroviruses among healthy population
A bispecific broadly neutralizing antibody against enterovirus 71 and coxsackievirus A16 with therapeutic potential
Bioinspired Artificial Nanodecoys for Hepatitis B Virus
Outer nuclear membrane fusion of adjacent nuclei in varicella-zoster virus-induced syncytia
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization
Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
A neonatal mouse model of coxsackievirus A10 infection for anti-viral evaluation
Herpes simplex virus type 1 abrogates the antiviral activity of Ch25h via its virion host shutoff protein
ORF7 of Varicella-Zoster Virus Is Required for Viral Cytoplasmic Envelopment in Differentiated Neuronal Cells
A novel combined vaccine based on monochimeric VLP co-displaying multiple conserved epitopes against enterovirus 71 and varicella-zoster virus
A novel toolbox for the in vitro assay of hepatitis D virus infection
A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice
Evaluation of immunity to varicella zoster virus with a novel double antigen sandwich enzyme-linked immunosorbent assay
A neonatal mouse model for the evaluation of antibodies and vaccines against coxsackievirus A6
An HBV-tolerant immunocompetent model that effectively simulates chronic hepatitis B virus infection in mice
Functional Analysis of Human Cytomegalovirus UL/b ' Region Using SCID-hu Mouse Model
Development and evaluation of rapid point-of-care tests for detection of Enterovirus 71 and Coxsackievirus A16 specific immunoglublin M antibodies
Detection and analysis of tupaia hepatocytes via mAbs against tupaia serum albumin
Modulation of host CD59 expression by varicella-zoster virus in human xenografts in vivo
A highly conserved epitope-vaccine candidate against varicella-zoster virus induces neutralizing antibodies in mice
Development of sandwich ELISAs that can distinguish different types of coxsackievirus A16 viral particles
Serological Evaluation of Immunity to the Varicella-Zoster Virus Based on a Novel Competitive Enzyme-Linked Immunosorbent Assay
Extensive phagocytosis in non-viral-infected neurons observed in enterovirus A 71-infected cases
Construction and characterization of an infectious clone of coxsackievirus A6 that showed high virulence in neonatal mice
Insights into the function of tegument proteins from the varicella zoster virus
Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo
A monoclonal antibody-based VZV glycoprotein E quantitative assay and its application on antigen quantitation in VZV vaccine
Analysis of Cross-Reactive Neutralizing Antibodies in Human HFMD Serum with an EV71 Pseudovirus-Based Assay
Development of a varicella-zoster virus neutralization assay using a glycoprotein K antibody enzyme-linked immunosorbent spot assay
Development of an Enzyme-Linked Immunosorbent Spot Assay To Measure Serum-Neutralizing Antibodies against Coxsackievirus B3
Protection against Lethal Enterovirus 71 Challenge in Mice by a Recombinant Vaccine Candidate Containing a Broadly Cross-Neutralizing Epitope within the VP2 EF Loop
The Cross-Neutralizing Activity of Enterovirus 71 Subgenotype C4 Vaccines in Healthy Chinese Infants and Children
Development of a novel baculovirus titration method using the Enzyme-linked immunosorbent spot (ELISPOT) assay
ORF7 of Varicella-Zoster Virus Is a Neurotropic Factor
Efficient inhibition of HIV-1 replication by an artificial polycistronic miRNA construct
RNA Interference inhibits Hepatitis B Virus of different genotypes in Vitro and in Vivo
Genome-Wide Mutagenesis Reveals That ORF7 Is a Novel VZV Skin-Tropic Factor
Performance of Detecting IgM Antibodies against Enterovirus 71 for Early Diagnosis
Tetracysteine as a Reporter for Gene Therapy
Immune response induced by a different combined immunization of HBsAg vaccine
Variants of green fluorescent protein GFPxm
Hydrophobicity of reactive site loop of SCCA1 affects its binding to hepatitis B virus
MicroRNA调控在溶瘤病毒疗法中的应用与展望
中国生物工程杂志,1671-8135,2024-01-25.水痘带状疱疹病毒ORF41的单克隆抗体制备及其初步研究
中国免疫学杂志,1000-484X,2023-05-10.致手足口病柯萨奇病毒A6型和A10型相关疫苗的研究进展
病毒学报,1000-8721,2023-05-09.水痘-带状疱疹病毒ORF43蛋白的单克隆抗体制备及初步研究
病毒学报,1000-8721,2021-08-17.厦门市健康人群肠道病毒D68型血清流行病学调查
病毒学报,1000-8721,2021-07-23.寨卡病毒衣壳蛋白单克隆抗体的制备及性能评价
中国病原生物学杂志,1673-5234,2020-08-30.水痘-带状疱疹病毒糖蛋白gE在昆虫细胞中的表达鉴定及其晶体培养
中国病原生物学杂志,1673-5234,2019-05-30.水痘-带状疱疹病毒主要衣壳蛋白ORF40单克隆抗体的制备及初步应用
中国免疫学杂志,1000-484X,2019-05-12.柯萨奇病毒A组6型抗体中和试验Nt-ELISPOT方法的建立
中国病原生物学杂志,1673-5234,2018-10-30.基于立即早期蛋白IE62建立水痘-带状疱疹病毒感染性滴度检测方法
中国免疫学杂志,1000-484X,2018.大肠杆菌可溶性表达人鳞状上皮细胞癌抗原的制备及应用
生物技术通报,1002-5464,2017.水痘-带状疱疹病毒糖蛋白N的单克隆抗体制备及初步研究
病毒学报,1000-8721,2017.以乙肝病毒核心蛋白为载体制备肠道病毒71型非结构蛋白3D单克隆抗体
中国免疫学杂志,1000-484X,2017.肠道病毒68型新型中和试验方法的建立及其初步应用
病毒学报,1000-8721,2017.水痘带状疱疹病毒皮层蛋白功能的研究进展
中国科学:生命科学,1674-7232,2015-07-20.高特异性人血清白蛋白化学发光免疫分析方法的建立
厦门大学学报(自然科学版),0438-0479,2014-05-28.靶向HIV-1vif的高效人工miRNA的构建及慢病毒介导的体外抗病毒研究
病毒学报,1000-8721,2010.靶向HIV-1pol的高效人工miRNA的构建与体外抗病毒能力评价
生物工程学报,1000-3061,2010.靶向HIV-1细胞受体基因CCR5的人工miRNA的构建与鉴定
厦门大学学报(自然科学版),0438-0479,2010.人乳头瘤病毒假病毒制备方法的优化
厦门大学学报(自然科学版) ,0438-0479,2009.重组慢病毒对不同哺乳动物细胞基因转移及表达效率的研究
厦门大学学报(自然科学版),0438-0479,2008-05-15.靶向HIV-1 vif的高效siRNA的筛选及慢病毒介导的体外抗病毒研究
病毒学报,1000-8721,2008-03-15.一种可药物筛选及体内检测的新型慢病毒基因治疗载体的构建
生物工程学报,1000-3061,2008-02-25.适于HIV-1 p24抗原检测试剂的单抗制备与筛选
中国人兽共患病学报,1002-2694,2007-06-15.应用离心方法提高杆状病毒对哺乳动物细胞转导实验效率
生物工程学报,1000-3061,2007-05-15.戊肝病毒Th表位肽免疫可增强其载体蛋白的体液免疫应答
生物工程学报,1000-3061,2007-03-30.人乳头瘤病毒16型假病毒中和实验的建立和初步应用
生物工程学报,1000-3061,2006-11-30.SARS冠状病毒核衣壳(N)蛋白不同区域的原核表达
病毒学报,1000-8721,2005-03-20.寨卡病毒NS2B蛋白的表达纯化及单克隆抗体制备
生物技术通讯,1009-0002,2020-01-30.埃可病毒25型新型中和实验方法的建立与应用
生物技术通讯,1009-0002,2016-01-30.肿瘤细胞特异启动子hTERT介导的靶向mdr1基因的RNAi用于逆转卵巢癌细胞MDR的研究
中国医学创新,1674-4985,2015-12-05.