已发表成果:
WOK 论文 38 篇;
SHP-1 Regulates CD8+T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay
MHC class II regulation of CD8+T cell tolerance and implications in autoimmunity and cancer immunotherapy
Spatial proteomics of immune microenvironment in nonalcoholic steatohepatitis-associated hepatocellular carcinoma
Ritanserin suppresses acute myeloid leukemia by inhibiting DGKα to downregulate phospholipase D and the Jak-Stat/MAPK pathway
Evaluation of DDA Library-Free Strategies for Phosphoproteomics and Ubiquitinomics Data-Independent Acquisition Data
Attenuated Salmonella blocks cancer metastasis by activating NK cells in an IFN-γ- dependent manner
Themis suppresses the effector function of CD8<SUP>+</SUP> T cells in acute viral infection
TMEM25 inhibits monomeric EGFR-mediated STAT3 activation in basal state to suppress triple-negative breast cancer progression
b2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function
Integration of Protein Nanocage with CpG Motifs: A Virus-Mimicked Core-Shell Nanostructure to Ignite Antitumor Immunity
A prophylactic effect of aluminium-based adjuvants against respiratory viruses via priming local innate immunity
Prediction of cardiovascular diseases mortality- and disability-adjusted life-years attributed to modifiable dietary risk factors from 1990 to 2030 among East Asian countries and the world
Revealing the evolution of the tumor immune microenvironment in follicular lymphoma patients progressing within 24 months using single-cell imaging mass cytometry
Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and synergizes with CTLA-4 or TIM-3 blockade
Themis is indispensable for IL-2 and IL-15 signaling in T cells
Glycogen synthase kinase 3 drives thymocyte egress by suppressing beta-catenin activation of Akt
IFN-gamma-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA
Preclinical evaluation of a regimen combining chidamide and ABT-199 in acute myeloid leukemia
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2
Apatinib exhibits cytotoxicity toward leukemia cells by targeting VEGFR2-mediated prosurvival signaling and angiogenesis
T cell receptor and cytokine signal integration in CD8(+) T cells is mediated by the protein Themis
Monoubiquitination of p120-catenin is essential for TGF beta-induced epithelial-mesenchymal transition and tumor metastasis
Thymic-specific regulation of TCR signaling by Tespa1
CCL4 enhances blinatumomab therapy in a human B-ALL xenograft mouse model
Glycogen synthase kinase 3 drives thymocyte egress by terminating tonic akt signaling
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies (vol 33, pg 2315, 2019)
Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies
Synthetic lethality of combined AT-101 with idarubicin in acute myeloid leukemia via blockade of DNA repair and activation of intrinsic apoptotic pathway
Patient's T Cell Functionality Determines Blinatumomab-Mediated Killing of B-ALL Leukemia Cells
Noninvasive photoacoustic and fluorescent tracking of optical dye labeled T cellular activities of diseased sites at new depth
A critical role of periostin in B-cell acute lymphoblastic leukemia
The RIP3-RIP1-NF-kappa B signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8(+) T cells
Differential Sensitivity of Target Genes to Translational Repression by miR-17 similar to 92
A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells
The role of Themis in T cell activation and effector function