PLCγ1 deficiency in chondrocytes accelerates the age-related changes in articular cartilage and subchondral bone

Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor a deficiency, associated with decreased ERK and Akt activation

Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study

Suppressing phosphoinositide-specific phospholipases C gamma 1 promotes mineralization of osteoarthritic subchondral bone osteoblasts via increasing autophagy, thereby ameliorating articular cartilage degeneration

The Relationship between Hepatic Myeloid-Derived Suppressor Cells and Clinicopathological Parameters in Patients with Chronic Liver Disease

PLC gamma 1 inhibition-driven autophagy of IL-1 beta-treated chondrocyte confers cartilage protection against osteoarthritis, involving AMPK, Erk and Akt

Suppressing PLC gamma 1 enhances osteogenic and chondrogenic potential of BMSCs

IL-1 beta receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes

Chondroprotection of PPAR alpha activation by WY14643 via autophagy involving Akt and ERK in LPS-treated mouse chondrocytes and osteoarthritis model

Depth-Resolved Enhanced Spectral-Domain OCT Imaging of Live Mammalian Embryos Using Gold Nanoparticles as Contrast Agent

Synthesis and structure-activity relationship of N-(piperidin-4-yl)benzamide derivatives as activators of hypoxia-inducible factor 1 pathways

The inhibition of PLC gamma 1 protects chondrocytes against osteoarthritis, implicating its binding to Akt