TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation

GIPC1 promotes tumor growth and migration in gastric cancer via activating PDGFR/PI3K/AKT signaling

Periostin-TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer

USP39 attenuates the antitumor activity of cisplatin on colon cancer cells dependent on p53

Ultrasound-driven nanoreactor with USP39 ShRNAi-intensified ferroptosis for synergistic sono-chemodynamic therapy

Isochlorogenic acid A alleviates dextran sulfate sodium-induced ulcerative colitis in mice through STAT3/NF-?B pathway

USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression

Protective effect and mechanism of loganin and morroniside on acute lung injury and pulmonary fibrosis

Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma

USP39 mediates p21-dependent proliferation and neoplasia of colon cancer cells by regulating the p53/p21/CDC2/cyclin B1 axis

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway

Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-kappa B pathway

Phosphoinositide specific phospholipase C gamma 1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1 alpha

Ubiquitin-specific peptidase 39 regulates the process of proliferation and migration of human ovarian cancer via p53/p21 pathway and EMT

Corilagin induces apoptosis, autophagy and ROS generation in gastric cancer cells in vitro

TNF-alpha and IFN-gamma synergistically inhibit the repairing ability of mesenchymal stem cells on mice colitis and colon cancer

Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy

Deficiency of periostin impairs liver regeneration in mice after partial hepatectomy

Phosphoinositide-specific phospholipase C gamma 1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling

Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4 alpha and contributes to cell cycle control in hepatoma cells

Lentivirus-mediated PLC gamma 1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma

Inhibitory effect of ursolic acid and oleanolic acid from Eriobotrya fragrans on A549 cell viability in vivo

Involvement of Wnt/beta-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma

Protein kinase B and extracellular signal-regulated kinase contribute to the chondroprotective effect of morroniside on osteoarthritis chondrocytes

Matrine inhibits proliferation and induces apoptosis via BID-mediated mitochondrial pathway in esophageal cancer cells

Involvement of BID Translocation in Glycyrrhetinic Acid and 11-Deoxy Glycyrrhetinic Acid-Induced Attenuation of Gastric Cancer Growth

Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor

Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium- Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-kappa B Activation

Twist2 promotes ovarian cancer cell survival through activation of Akt

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway

Bid-overexpression regulates proliferation and phosphorylation of Akt and MAPKs in response to etoposide-induced DNA damage in hepatocellular carcinoma cells

17 beta-ESTRADIOL PROMOTES CELL PROLIFERATION IN RAT OSTEOARTHRITIS MODEL CHONDROCYTES VIA PI3K/AKT PATHWAY

p53 Facilitates BH3-only BID nuclear export to induce apoptosis in the irrepairable DNA damage response

Ginsenoside Compound K Attenuates Metastatic Growth of Hepatocellular Carcinoma, which Is Associated with the Translocation of Nuclear Factor-kappa B p65 and Reduction of Matrix Metalloproteinase-2/9

Intestinal metabolite compound K of ginseng saponin potently attenuates metastatic growth of hepatocellular carcinoma by augmenting apoptosis via a bid-mediated mitochondrial pathway

Bid Stands at the Crossroad of Stress-Response Pathways

Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways

Upregulated expression of periostin by hypoxia in non-small-cell lung cancer cells promotes cell survival via the Akt/PKB pathway

Role of Hypoxia in the Hallmarks of Human Cancer

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1 alpha up-regulation and MMP9 activation

Osteopontin Prevents Curcumin-Induced Apoptosis and Promotes Survival Through Akt Activation via alpha(v)beta(3) Integrins in Human Gastric Cancer Cells

Osteopontin promotes ovarian cancer progression and cell survival and increases HIF-1 alpha expression through the PI3-K/Akt pathway