学者信息

吴川六 (ChuanLiu Wu)

化学化工学院

ResearcherID:B-1820-2012

合作者

已发表成果:

WOK 论文 52 篇;其它论文 4 篇;专利发明 4 个;

  • Ribosomal translation of fluorinated non-canonical amino acids for <i>de novo</i> biologically active fluorinated macrocyclic peptides

    CHEMICAL SCIENCE,2041-6520,2024-08-02.
    Wu, Junjie; Wang, Yuchan; Cai, Wenfeng; Chen, Danyan; Peng, Xiangda; Dong, Huilei; Li, Jinjing; Liu...
    WOS:001286610500001   EI:20243316872113   10.1039/d4sc04061a
    收录情况:SCIE、EI
  • Ribosomal Incorporation of Lithocholic Acid into Peptides for the <i>De Novo</i> Discovery Of Peptide-Lithocholic Acid Hybrid Macrocyclic Peptides

    ACS CHEMICAL BIOLOGY,1554-8929,2024-06-20.
    Song, Lulu; Liu, Hongtan; Li, Maolin; Yang, Yawen; Dong, Huilei; Li, Jinjing; Shao, Jiaqi; Zhi, Lix...
    WOS:001252054100001   10.1021/acschembio.4c00298
    收录情况:SCIE
  • Recent advances in chemical protein synthesis: method developments and biological applications

    SCIENCE CHINA-CHEMISTRY,1674-7291,2024-03-12.
    Dong, Suwei; Zheng, Ji-Shen; Li, Yiming; Wang, Huan; Chen, Gong; Chen, Yongxiang; Fang, Gemin; Guo,...
    WOS:001185512500001   EI:20241215759776   10.1007/s11426-024-1950-1
    收录情况:SCIE、EI
  • Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X<sub>L</sub> by engaging a single-residue discrepancy

    NATURE COMMUNICATIONS,,2024-02-17.
    Li, Fengwei; Liu, Junjie; Liu, Chao; Liu, Ziyan; Peng, Xiangda; Huang, Yinyue; Chen, Xiaoyu; Sun, X...
    WOS:001163800700026   10.1038/s41467-024-45848-1
    收录情况:SCIE
  • Selection and evolution of disulfide-rich peptides <i>via</i> cellular protein quality control

    CHEMICAL SCIENCE,2041-6520,2023-03.
    Meng, Xiaoting; Xu, Chaoying; Fan, Shihui; Dong, Meng; Zhuang, Jie; Duan, Zengping; Zhao, Yibing; W...
    WOS:000948893800001   EI:20231313813219   10.1039/d2sc05343h
    收录情况:SCIE、EI
  • De Novo Discovery of Cysteine Frameworks for Developing Multicyclic Peptide Libraries for Ligand Discovery

    Journal of the American Chemical Society,0002-7863,2023.
    Li, Jinjing; Liu, Hongtan; Xiao, Shuling; Fan, Shihui; Cheng, Xueting; Wu, Chuanliu
    WOS:001133415500001   EI:20235215293396   10.1021/jacs.3c11856
    收录情况:SCIE、EI
  • Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery

    CHEMICAL SCIENCE,2041-6520,2022-05.
    Wu, Yapei; Fan, Shihui; Dong, Meng; Li, Jinjing; Kong, Chuilian; Zhuang, Jie; Meng, Xiaoting; Lu, S...
    WOS:000797851800001   EI:20223112450567   10.1039/d2sc00924b
    收录情况:SCIE、EI
  • De novo design and directed folding of disulfide-bridged peptide heterodimers

    NATURE COMMUNICATIONS,,2022-03-22.
    Yao, Sicong; Moyer, Adam; Zheng, Yiwu; Shen, Yang; Meng, Xiaoting; Yuan, Chong; Zhao, Yibing; Yao, ...
    WOS:000772173000002   10.1038/s41467-022-29210-x
    收录情况:SCIE
  • Design and Ribosomal Incorporation of Noncanonical Disulfide-Directing Motifs for the Development of Multicyclic PeptideLibraries br

    Journal of the American Chemical Society,0002-7863,2022.
    Dong, Huilei; Li, Jinjing; Liu, Hongtan; Lu, Shuaimin; Wu, Junjie; Zhang, Youming; Yin, Yizhen; Zha...
    WOS:000777169400047   EI:20221311867493   10.1021/jacs.2c00216
    收录情况:SCIE、EI
  • Redox-Regulated Conformational Change of Disulfide-Rich Assembling Peptides

    Angewandte Chemie - International Edition,1433-7851,2022.
    Dong, Huilei; Wang, Mingshui; Fan, Shihui; Wu, Chuanliu; Zhang, Chunhui; Wu, Xia; Xue, Bin; Cao, Yi...
    WOS:000863942700001   EI:20224112848730   10.1002/anie.202212829
    收录情况:SCIE、EI
  • Fast and Selective Reaction of 2-Benzylacrylaldehyde with 1,2-Aminothiol for Stable N-Terminal Cysteine Modification and Peptide Cyclization

    BIOCONJUGATE CHEMISTRY,1043-1802,2021-09-15.
    Wu, Yaqi; Li, Cong; Fan, Shihui; Zhao, Yibing; Wu, Chuanliu
    WOS:000697280800013   EI:20220411529601   10.1021/acs.bioconjchem.1c00378
    收录情况:SCIE、EI
  • An evolution-inspired strategy to design disulfide-rich peptides tolerant to extensive sequence manipulation

    Chemical Science,2041-6520,2021-09-14.
    Zha, Jun; Li, Jinjing; Fan, Shihui; Duan, Zengping; Zhao, Yibing; Wu, Chuanliu
    WOS:000679994700001   EI:20213610866866   10.1039/d1sc02952e
    收录情况:SCIE、EI
  • Directed Disulfide Pairing and Folding of Peptides for the De Novo Development of Multicyclic Peptide Libraries

    Journal of the American Chemical Society,0002-7863,2020-09-23.
    Lu, Shuaimin; Wu, Yapei; Li, Jinjing; Meng, Xiaoting; Hu, Chenliang; Zhao, Yibing; Wu, Chuanliu
    WOS:000575684100023   EI:20204109319675   10.1021/jacs.0c06044
    收录情况:SCIE、EI
  • Design and Synthesis of Disulfide-Rich Peptides with Orthogonal Disulfide Pairing Motifs

    Journal of Organic Chemistry,0022-3263,2020-09-04.
    Huang, Zirong; Wu, Yapei; Dong, Huilei; Zhao, Yibing; Wu, Chuanliu
    WOS:000569376800040   EI:20204109329876   10.1021/acs.joc.0c01600
    收录情况:SCIE、EI
  • Biocompatible and Rapid Cyclization of Peptides with 2,4-Difluoro-6-hydroxy-1,3,5-benzenetricarbonitrile for the Development of Cyclic Peptide Libraries

    BIOCONJUGATE CHEMISTRY,1043-1802,2020-09.
    Zheng, Xuejun; Liu, Weidong; Liu, Ziyan; Zhao, Yibing; Wu, Chuanliu
    WOS:000573368500005   EI:20220411528205   10.1021/acs.bioconjchem.0c00363
    收录情况:SCIE、EI
  • Condensation of 2-((Alkylthio)(aryl)methylene)malononitrile with 1,2-Aminothiol as a Novel Bioorthogonal Reaction for Site-Specific Protein Modification and Peptide Cyclization

    Journal of the American Chemical Society,0002-7863,2020.
    Zheng, Xiaoli; Li, Zhuoru; Gao, Wei; Meng, Xiaoting; Li, Xuefei; Luk, Louis Y. P.; Zhao, Yibing; Ts...
    WOS:000526392600022   EI:20201108296352   10.1021/jacs.9b11875
    收录情况:SCIE、EI
  • Stabilizing p-Dithiobenzyl Urethane Linkers without Rate-Limiting Self-Immolation for Traceless Drug Release

    CHEMMEDCHEM,1860-7179,2019-06-18.
    Zheng, YW; Shen, Y; Meng, XT; Wu, YQ; Zhao, YB; Wu, CL
    WOS:000471896000007   10.1002/cmdc.201900248
    收录情况:SCIE
  • Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns

    CHEMBIOCHEM,1439-4227,2019-06-14.
    Lin, P; Yao, HW; Zha, J; Zhao, YB; Wu, CL
    WOS:000471712800005   10.1002/cbic.201800788
    收录情况:SCIE
  • A Doubly-Quenched Fluorescent Probe for Low-Background Detection of Mitochondrial H2O2

    ANALYTICAL CHEMISTRY,0003-2700,2019-05-21.
    Liu, J; Liang, JJ; Wu, CL; Zhao, YB
    WOS:000469304300069   EI:20220311479777   10.1021/acs.analchem.9b01294
    收录情况:SCIE、EI
  • Design and Synthesis of Cross-Link-Dense Peptides by Manipulating Regioselective Bisthioether Cross-Linking and Orthogonal Disulfide Pairing

    Journal of Organic Chemistry,0022-3263,2019-05-03.
    Dong, Huilei (1); Meng, Xiaoting (1); Zheng, Xiaoli (1); Cheng, Xueting (1); Zheng, Yiwu (1); Zhao,...
    WOS:000467319600023   EI:20191906894038   10.1021/acs.joc.9b00164
    收录情况:SCIE、EI
  • Interchain doubly-bridged alpha-helical peptides for the development of protein binders

    CHINESE CHEMICAL LETTERS,1001-8417,2019-04.
    Chen, YQ; Liang, JJ; Li, T; Lin, P; Zhao, YB; Wu, CL
    WOS:000468254500020   10.1016/j.cclet.2019.02.013
    收录情况:SCIE
  • CXC-Mediated Cellular Uptake of Miniproteins: Forsaking "Arginine Magic"

    ACS CHEMICAL BIOLOGY,1554-8929,2018-11.
    Meng, XT; Li, T; Zhao, YB; Wu, CL
    WOS:000451100800007   10.1021/acschembio.8b00564
    收录情况:SCIE
  • Multicyclic peptides constrained through noncanonical disulfide bonds and thioether crosslinks

    JOURNAL OF PEPTIDE SCIENCE,1075-2617,2018-09.
    Wu, CL
    WOS:000447650300012  
    收录情况:SCIE
  • A mini-review and perspective on multicyclic peptide mimics of antibodies

    CHINESE CHEMICAL LETTERS,1001-8417,2018-07.
    Liu, WD; Wu, CL
    WOS:000438004700011   10.1016/j.cclet.2018.03.015
    收录情况:SCIE
  • Celebrating the work of Young Thousand Talents Plan researchers

    ORGANIC & BIOMOLECULAR CHEMISTRY,1477-0520,2018-06-07.
    Jiang, XF; Wu, CL; Li, G; Song, QL; Luan, XJ; Lu, Z
    WOS:000434260600001   10.1039/c8ob90069h
    收录情况:SCIE
  • A phage display-based strategy for the de novo creation of disulfide-constrained and isomer-free bicyclic peptide affinity reagents

    CHEMICAL COMMUNICATIONS,1359-7345,2018-04-18.
    Zha, MR; Lin, P; Yao, HW; Zhao, YB; Wu, CL
    WOS:000435250100026   10.1039/c7cc09142g
    收录情况:SCIE
  • Plasmon-Enhanced Ultrasensitive Surface Analysis Using Ag Nanoantenna

    Analytical Chemistry,0003-2700,2018-02-06.
    Li, Chao-Yu(1); Gao, Jin-Hong(1); Yi, Jun(1); Zhang, Xia-Guang(1); Cao, Xiao-Dan(2); Meng, Meng(1);...
    WOS:000424730600076   EI:20180704780689   10.1021/acs.analchem.7b04113
    收录情况:SCIE、EI
  • De novo design of constrained and sequence-independent peptide scaffolds with topologically-formidable disulfide connectivities

    Chemical Science,2041-6520,2018.
    Zheng, Yiwu(1); Meng, Xiaoting(1); Wu, Yaqi(1); Zhao, Yibing(1); Wu, Chuanliu(1)
    WOS:000422947000003   EI:20180404678235   10.1039/c7sc03956e
    收录情况:SCIE、EI
  • A lysosome-locating and acidic pH-activatable fluorescent probe for visualizing endogenous H2O2 in lysosomes

    ANALYST,0003-2654,2017-12-07.
    Liu, Jun; Zhou, Shunqing; Ren, Jing; Wu, Chuanliu; Zhao, Yibing
    WOS:000415866200020   10.1039/c7an01280b
    收录情况:SCIE
  • Proteolytic Unlocking of Ultrastable Twin-Acylhydrazone Linkers for Lysosomal Acid-Triggered Release of Anticancer Drugs

    BIOCONJUGATE CHEMISTRY,1043-1802,2017-10.
    Zheng, Yiwu; Ren, Jing; Wu, Yaqi; Meng, Xiaoting; Zhao, Yibing; Wu, Chuanliu
    WOS:000413503400015   EI:20220411526168   10.1021/acs.bioconjchem.7b00471
    收录情况:SCIE、EI
  • Biscysteine-Bearing Peptide Probes to Reveal Extracellular Thiol-Disulfide Exchange Reactions Promoting Cellular Uptake

    Analytical Chemistry,0003-2700,2017-08-15.
    Li, Tao(1); Gao, Wei(1); Liang, Jingjing(1); Zha, Mirao(1); Chen, Yaqi(1); Zhao, Yibing(1); Wu, Chu...
    WOS:000407988600046   EI:20173404055360   10.1021/acs.analchem.7b02084
    收录情况:SCIE、EI
  • Tunable accessibility of dye-doped liposomes towards gold nanoparticles for fluorescence sensing of lipopolysaccharide

    ANALYST,0003-2654,2017-04-07.
    Gao, Jinhong; Li, Zhuoru; Zhang, Ouyang; Wu, Chuanliu; Zhao, Yibing
    WOS:000400689100008   10.1039/c7an00019g
    收录情况:SCIE
  • Thioether-Bonded Fluorescent Probes for Deciphering Thiol-Mediated Exchange Reactions on the Cell Surface

    ANALYTICAL CHEMISTRY,0003-2700,2017-01-03.
    Gao, Wei; Li, Tao; Wang, Jinghui; Zhao, Yibing; Wu, Chuanliu
    WOS:000391346600086   10.1021/acs.analchem.6b04096
    收录情况:SCIE
  • Stabilization of peptides against proteolysis through disulfide-bridged conjugation with synthetic aromatics

    Organic and Biomolecular Chemistry,1477-0520,2017.
    Chen, Yaqi(1); Li, Tao(1); Li, Jianguo(2,3); Cheng, Shiyan(1); Wang, Jinghui(1); Verma, Chandra(3,4...
    WOS:000395884000020   EI:20170903400693   10.1039/c6ob02786e
    收录情况:SCIE、EI
  • Precisely Regulated and Efficient Locking of Linear Peptides into Stable Multicyclic Topologies through a One-Pot Reaction

    Angewandte Chemie - International Edition,1433-7851,2017.
    Liu, Weidong(1); Zheng, Yiwu(1); Kong, Xudong(2); Heinis, Christian(2); Zhao, Yibing(1); Wu, Chuanl...
    WOS:000398154000007   EI:20170903395915   10.1002/anie.201610942
    收录情况:SCIE、EI
  • Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers

    CHEMICAL SCIENCE,2041-6520,2017 .
    Zheng, Yiwu; Li, Zhuoru; Ren, Jing; Liu, Weidong; Wu, Yaqi; Zhao, Yibing; Wu, Chuanliu
    WOS:000397560500005   EI:20171403518542   10.1039/c6sc05710a
    收录情况:SCIE、EI
  • Peptide Macrocycles Developed from Precisely Regulated Multiple Cyclization of Unprotected Peptides

    Chemistry - A European Journal,0947-6539,2017.
    Wang, Jinghui(1); Zha, Mirao(1); Fei, Qianran(1); Liu, Weidong(1); Zhao, Yibing(1); Wu, Chuanliu(1)
    WOS:000413768900026   EI:20174104252704   10.1002/chem.201703139
    收录情况:SCIE、EI
  • Inside Cover: Metal–Organic-Framework-Templated Polyelectrolyte Nanocapsules for the Encapsulation and Delivery of Small-Molecule–Polymer Conjugates (Chem. Asian J. 12/2016)

    Chemistry - An Asian Journal,1861-4728,2016-06-21.
    Liu, Shuo(1); Chen, Jianbin(1); Bao, Xiaojia(1); Li, Tao(1); Ling, Yunyang(1); Li, Chunxiang(1); Wu...
    EI:20162702567520   10.1002/asia.201600788
    收录情况:EI
  • PH-Switchable Fluorescent Probe for Spatially-Confined Visualization of Intracellular Hydrogen Peroxide

    Analytical Chemistry,0003-2700,2016-06-07.
    Liu, Jun(1); Ren, Jing(1); Bao, Xiaojia(1); Gao, Wei(1); Wu, Chuanliu(1); Zhao, Yibing(1)
    WOS:000377631000045   EI:20162402503752   10.1021/acs.analchem.6b00654
    收录情况:SCIE、EI
  • Aromaticity/Bulkiness of Surface Ligands to Promote the Interaction of Anionic Amphiphilic Gold Nanoparticles with Lipid Bilayers

    Langmuir,0743-7463,2016-02-16.
    Gao, Jinhong(1); Zhang, Ouyang(1); Ren, Jing(1); Wu, Chuanliu(1); Zhao, Yibing(1)
    WOS:000370454100020   EI:20160801998233   10.1021/acs.langmuir.6b00035
    收录情况:SCIE、EI
  • POEGMA-based disulfide-containing fluorescent probes for imitating and tracing noninternalization-based intracellular drug delivery

    CHEMICAL COMMUNICATIONS,1359-7345,2016.
    Ling, Yunyang; Ren, Jing; Li, Tao; Zhao, Yibing; Wu, Chuanliu
    WOS:000372174700025   10.1039/c6cc00369a
    收录情况:SCIE
  • Metal-Organic-Framework-Templated Polyelectrolyte Nanocapsules for the Encapsulation and Delivery of Small-Molecule-Polymer Conjugates

    Chemistry - An Asian Journal,1861-4728,2016.
    Liu, Shuo(1); Chen, Jianbin(1); Bao, Xiaojia(1); Li, Tao(1); Ling, Yunyang(1); Li, Chunxiang(1); Wu...
    WOS:000379519400011   EI:20162302467907   10.1002/asia.201600250
    收录情况:SCIE、EI
  • Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,0002-7863,2015-12-09.
    Zheng, Yiwu; Zhai, Linxiang; Zhao, Yibing; Wu, Chuanliu
    WOS:000366339900009   10.1021/jacs.5b10779
    收录情况:SCIE
  • The Interplay of Disulfide Bonds, alpha-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides

    BIOMACROMOLECULES,1525-7797,2015-08.
    Chen, Yaqi; Yang, Chaoqiong; Li, Tao; Zhang, Miao; Liu, Yang; Gauthier, Marc A.; Zhao, Yibing; Wu, ...
    WOS:000359499500011   EI:20153301169333   10.1021/acs.biomac.5b00567
    收录情况:SCIE、EI
  • Conjugated copolymer-photosensitizer molecular hybrids with broadband visible light absorption for efficient light-harvesting and enhanced singlet oxygen generation

    Journal of Materials Chemistry C,2050-7534,2015-02-07.
    He, Rongkun(1); Hu, Ming(1); Xu, Ting(1); Li, Chunxiang(1); Wu, Chuanliu(1); Guo, Xiangqun(1); Zhao...
    WOS:000348300300008   EI:20150500465808   10.1039/c4tc02568g
    收录情况:SCIE、EI
  • Multivalent peptides displayed on OEGMA-based copolymers for the modulation of protein-protein interactions

    POLYMER CHEMISTRY,1759-9954,2015.
    Li, Yujie; Li, Tao; Wang, Jinghui; Bao, Xiaojia; Zhao, Yibing; Wu, Chuanliu
    WOS:000364923400010   EI:20154701569994   10.1039/c5py01080b
    收录情况:SCIE、EI
  • Exploring and Exploiting Dynamic Noncovalent Chemistry for Effective Surface Modification of Nanoscale Metal-Organic Frameworks

    ACS APPLIED MATERIALS & INTERFACES,1944-8244,2014-04-23.
    Liu, Shuo; Zhai, Linxiang; Li, Chunxiang; Li, Yujie; Guo, Xiangqun; Zhao, Yibing; Wu, Chuanliu
    WOS:000335086000012   EI:20141917690108   10.1021/am500192b
    收录情况:SCIE、EI
  • Exploration of the growth process of ultrathin silica shells on the surface of gold nanorods by the localized surface plasmon resonance

    NANOTECHNOLOGY,0957-4484,2014-01-31.
    Li, Chong; Li, Yujie; Ling, Yunyang; Lai, Yangwei; Wu, Chuanliu; Zhao, Yibing
    WOS:000329464000014   EI:20140317203580   10.1088/0957-4484/25/4/045704
    收录情况:SCIE、EI
  • Exploring and exploiting the synergy of non-covalent interactions on the surface of gold nanoparticles for fluorescent turn-on sensing of bacterial lipopolysaccharide

    Nanoscale,2040-3364,2013-09-07.
    Gao, Jinhong(1); Lai, Yangwei(1); Wu, Chuanliu(1); Zhao, Yibing(1)
    WOS:000322958800075   EI:20133416639571   10.1039/c3nr02490c
    收录情况:SCIE、EI
  • A facile and general approach for the synthesis of fluorescent silica nanoparticles doped with inert dyes

    Chinese Science Bulletin,1001-6538,2011-09.
    Mu Xue; Wu ChuanLiu; Lai JinPing; Chen JianBin; Zheng JinSheng; Li Chong; Zhao YiBing
    WOS:000296640800003   10.1007/s11434-011-4727-1
    收录情况:SCIE
  • Extracting fluorescence signal due to direct excitation of the energy acceptor from quantum dot-based FRET

    Journal of Nanoparticle Research,1388-0764,2010-08.
    Huang, Chaobiao(1); Wu, Chuanliu(2); Zhao, Yibing(2)
    WOS:000280240600021   EI:20103113107877   10.1007/s11051-009-9777-9
    收录情况:SCIE、EI
  • LSPR sensing of molecular biothiols based on noncoupled gold nanorods

    Langmuir,0743-7463,2010-06-01.
    Li, Chong(1); Wu, Chuanliu(1); Zheng, Jinsheng(1); Lai, Jinping(1); Zhang, Chenlong(1); Zhao, Yibin...
    WOS:000277928100196   EI:20102212969973   10.1021/la101285r
    收录情况:SCIE、EI
  • 基于细胞表面二硫键交换反应实现多肽分子探针的高效跨膜递送

    中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.
    李涛;赵一兵;吴川六
  • 人造二硫键骨架精确制导多肽分子氧化折叠及折叠机制探索

    中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.
    郑艺武;吴雅琪;赵一兵;吴川六
  • 构型固定的环肽分子探针构建及蛋白质相互作用调控研究

    中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.
    刘威东;郑艺武;李涛;陈亚骐;吴川六
  • 结合荧光标记脂质体与两亲性金纳米颗粒构建高效脂多糖检测体系

    全国环境纳米技术及生物效应学术研讨会摘要集,,2016-04-08.
    高锦鸿;吴川六;赵一兵