已发表成果:
WOK 论文 52 篇;其它论文 4 篇;专利发明 4 个;
Ribosomal translation of fluorinated non-canonical amino acids for <i>de novo</i> biologically active fluorinated macrocyclic peptides
Ribosomal Incorporation of Lithocholic Acid into Peptides for the <i>De Novo</i> Discovery Of Peptide-Lithocholic Acid Hybrid Macrocyclic Peptides
Recent advances in chemical protein synthesis: method developments and biological applications
Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X<sub>L</sub> by engaging a single-residue discrepancy
Selection and evolution of disulfide-rich peptides <i>via</i> cellular protein quality control
De Novo Discovery of Cysteine Frameworks for Developing Multicyclic Peptide Libraries for Ligand Discovery
Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery
De novo design and directed folding of disulfide-bridged peptide heterodimers
Design and Ribosomal Incorporation of Noncanonical Disulfide-Directing Motifs for the Development of Multicyclic PeptideLibraries br
Redox-Regulated Conformational Change of Disulfide-Rich Assembling Peptides
Fast and Selective Reaction of 2-Benzylacrylaldehyde with 1,2-Aminothiol for Stable N-Terminal Cysteine Modification and Peptide Cyclization
An evolution-inspired strategy to design disulfide-rich peptides tolerant to extensive sequence manipulation
Directed Disulfide Pairing and Folding of Peptides for the De Novo Development of Multicyclic Peptide Libraries
Design and Synthesis of Disulfide-Rich Peptides with Orthogonal Disulfide Pairing Motifs
Biocompatible and Rapid Cyclization of Peptides with 2,4-Difluoro-6-hydroxy-1,3,5-benzenetricarbonitrile for the Development of Cyclic Peptide Libraries
Condensation of 2-((Alkylthio)(aryl)methylene)malononitrile with 1,2-Aminothiol as a Novel Bioorthogonal Reaction for Site-Specific Protein Modification and Peptide Cyclization
Stabilizing p-Dithiobenzyl Urethane Linkers without Rate-Limiting Self-Immolation for Traceless Drug Release
Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns
A Doubly-Quenched Fluorescent Probe for Low-Background Detection of Mitochondrial H2O2
Design and Synthesis of Cross-Link-Dense Peptides by Manipulating Regioselective Bisthioether Cross-Linking and Orthogonal Disulfide Pairing
Interchain doubly-bridged alpha-helical peptides for the development of protein binders
CXC-Mediated Cellular Uptake of Miniproteins: Forsaking "Arginine Magic"
Multicyclic peptides constrained through noncanonical disulfide bonds and thioether crosslinks
A mini-review and perspective on multicyclic peptide mimics of antibodies
Celebrating the work of Young Thousand Talents Plan researchers
A phage display-based strategy for the de novo creation of disulfide-constrained and isomer-free bicyclic peptide affinity reagents
Plasmon-Enhanced Ultrasensitive Surface Analysis Using Ag Nanoantenna
De novo design of constrained and sequence-independent peptide scaffolds with topologically-formidable disulfide connectivities
A lysosome-locating and acidic pH-activatable fluorescent probe for visualizing endogenous H2O2 in lysosomes
Proteolytic Unlocking of Ultrastable Twin-Acylhydrazone Linkers for Lysosomal Acid-Triggered Release of Anticancer Drugs
Biscysteine-Bearing Peptide Probes to Reveal Extracellular Thiol-Disulfide Exchange Reactions Promoting Cellular Uptake
Tunable accessibility of dye-doped liposomes towards gold nanoparticles for fluorescence sensing of lipopolysaccharide
Thioether-Bonded Fluorescent Probes for Deciphering Thiol-Mediated Exchange Reactions on the Cell Surface
Stabilization of peptides against proteolysis through disulfide-bridged conjugation with synthetic aromatics
Precisely Regulated and Efficient Locking of Linear Peptides into Stable Multicyclic Topologies through a One-Pot Reaction
Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers
Peptide Macrocycles Developed from Precisely Regulated Multiple Cyclization of Unprotected Peptides
Inside Cover: Metal–Organic-Framework-Templated Polyelectrolyte Nanocapsules for the Encapsulation and Delivery of Small-Molecule–Polymer Conjugates (Chem. Asian J. 12/2016)
PH-Switchable Fluorescent Probe for Spatially-Confined Visualization of Intracellular Hydrogen Peroxide
Aromaticity/Bulkiness of Surface Ligands to Promote the Interaction of Anionic Amphiphilic Gold Nanoparticles with Lipid Bilayers
POEGMA-based disulfide-containing fluorescent probes for imitating and tracing noninternalization-based intracellular drug delivery
Metal-Organic-Framework-Templated Polyelectrolyte Nanocapsules for the Encapsulation and Delivery of Small-Molecule-Polymer Conjugates
Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides
The Interplay of Disulfide Bonds, alpha-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides
Conjugated copolymer-photosensitizer molecular hybrids with broadband visible light absorption for efficient light-harvesting and enhanced singlet oxygen generation
Multivalent peptides displayed on OEGMA-based copolymers for the modulation of protein-protein interactions
Exploring and Exploiting Dynamic Noncovalent Chemistry for Effective Surface Modification of Nanoscale Metal-Organic Frameworks
Exploration of the growth process of ultrathin silica shells on the surface of gold nanorods by the localized surface plasmon resonance
Exploring and exploiting the synergy of non-covalent interactions on the surface of gold nanoparticles for fluorescent turn-on sensing of bacterial lipopolysaccharide
LSPR sensing of molecular biothiols based on noncoupled gold nanorods
基于细胞表面二硫键交换反应实现多肽分子探针的高效跨膜递送
中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.人造二硫键骨架精确制导多肽分子氧化折叠及折叠机制探索
中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.构型固定的环肽分子探针构建及蛋白质相互作用调控研究
中国化学会第30届学术年会摘要集-第四分会:生物分析和生物传感,,2016-07-01.结合荧光标记脂质体与两亲性金纳米颗粒构建高效脂多糖检测体系
全国环境纳米技术及生物效应学术研讨会摘要集,,2016-04-08.