AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of <i>NLR</i>-associated autoinflammatory diseases

Sensing of mitochondrial DNA by ZBP1 promotes RIPK3-mediated necroptosis and ferroptosis in response to diquat poisoning

Acetylation is required for full activation of the NLRP3 inflammasome

Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

The miR-17～92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation

Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity

A p38 alpha-BLIMP1 signalling pathway is essential for plasma cell differentiation

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Impaired interferon-gamma signaling promotes the development of silicosis

Z-DNA binding protein 1 promotes heatstroke-induced cell death

N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

Glycogen synthase kinase 3 drives thymocyte egress by suppressing beta-catenin activation of Akt

YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3

SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA

RNA N-6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m(6)A-GLUT1-mTORC1 Axis and Is a Therapeutic Target

A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade

Macrophage p38 alpha promotes nutritional steatohepatitis through M1 polarization (vol 71, pg 163, 2019)

RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis

Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase

Gut stem cell necroptosis by genome instability triggers bowel inflammation

The role of type 1 interferons in coagulation induced by gram-negative bacteria

Generation of a murine SWATH-MS spectral library to quantify more than 11,000 proteins

Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure

Caspase-11 signaling enhances graft-versus-host disease

Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK

Macrophage p38 alpha promotes nutritional steatohepatitis through M1 polarization

High mobility group box 1 enables bacterial lipids to trigger receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis and apoptosis in mice

Biallelic mutations in PMFBP1 cause acephalic spermatozoa

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD

p38 alpha has an important role in antigen cross-presentation by dendritic cells

RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

The RIP3-RIP1-NF-kappa B signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8(+) T cells

Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression