已发表成果:
WOK 论文 71 篇;中文核心 3 篇;其它论文 2 篇;专利发明 3 个;
Risedronate-functionalized manganese-hydroxyapatite amorphous particles: A potent adjuvant for subunit vaccines and cancer immunotherapy
Rational design of a cross-type HPV vaccine through immunodominance shift guided by a cross-neutralizing antibody
SurfPro-NN: A 3D point cloud neural network for the scoring of protein-protein docking models based on surfaces features and protein language models
Redeveloping antigen detection kits for the diagnosis of rat hepatitis E virus
Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection
The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors
Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant
Evolving spike mutations in SARS-CoV-2 Omicron variants facilitate evasion from breakthrough infection-acquired antibodies
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
Risedronate-Functionalized Manganese-Calcium Phosphate Nanoparticles: A Potent Adjuvant for Subunit Vaccines and Cancer Immunotherapy
Structure and proposed DNA delivery mechanism of a marine roseophage
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16
Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for <i>Escherichia coli</i>-based vaccine design
Omics-guided bacterial engineering of Escherichia coli ER2566 for recombinant protein expression
Characterization of an Escherichia coli-derived triple-type chimeric vaccine against human papillomavirus types 39, 68 and 70
A bacterially expressed triple-type chimeric vaccine against human papillomavirus types 51, 69, and 26
Potential of conserved antigenic sites in development of universal SARS-like coronavirus vaccines
Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail
Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses
Endodomain truncation of the HIV-1 envelope protein improves the packaging efficiency of pseudoviruses
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
Structures of pseudorabies virus capsids
Cross-species tropism and antigenic landscapes of SARS-CoV-2 variants
A stepwise docking molecular dynamics approach for simulating antibody recognition with substantial conformational changes
Engineering for an HPV 9-valent vaccine candidate using genomic constitutive over-expression and low lipopolysaccharide levels in Escherichia coli cells
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors
Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids
Genome re-sequencing and reannotation of the Escherichia coli ER2566 strain and transcriptome sequencing under overexpression conditions
Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles
Recent Progress on the Versatility of Virus-Like Particles
Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
Viral neutralization by antibody-imposed physical disruption
HIV-1 Membrane-Proximal External Region Fused to Diphtheria Toxin Domain-A Elicits 4E10-Like Antibodies in Mice
Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development
Ferritin nanocage-based antigen delivery nanoplatforms: Epitope engineering for peptide vaccine design
Construction of a bacterial surface display system based on outer membrane protein F
Hepatitis E vaccine candidate harboring a non-particulate immunogen of E2 fused with CRM197 fragment A
Characterization of native-like HIV-1 gp140 glycoprotein expressed in insect cells
Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection
Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency
Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10
Identification of Strategic Residues at the Interface of Antigen-Antibody Interactions by In Silico Mutagenesis
Characterization of capsid protein (p495) of hepatitis E virus expressed ID in Escherichia coli and assembling into particles in vitro
A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses
Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
A novel combined vaccine based on monochimeric VLP co-displaying multiple conserved epitopes against enterovirus 71 and varicella-zoster virus
Stop codon mutagenesis for homogenous expression of human papillomavirus L1 protein in Escherichia coli
Using a Machine-Learning Approach to Predict Discontinuous Antibody-Specific B-Cell Epitopes
A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice
A shared N-terminal hydrophobic tail for the formation of nanoparticulates
The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction
In vitro affinity maturation and characterization of anti-P24 antibody for HIV diagnostic assay
Molecular insights into the inhibition of HIV-1 infection using a CD4 domain-1-specific monoclonal antibody
Identification of a Highly Conserved and Surface Exposed B-cell Epitope on the Nucleoprotein of Influenza A Virus
Bacteria expressed hepatitis E virus capsid proteins maintain virion-like epitopes
Protection against Lethal Enterovirus 71 Challenge in Mice by a Recombinant Vaccine Candidate Containing a Broadly Cross-Neutralizing Epitope within the VP2 EF Loop
Virus-like particle-based human vaccines: Quality assessment based on structural and functional properties
Role of heat-shock protein 90 in hepatitis E virus capsid trafficking
Molecular and Phylogenetic Analyses Suggest an Additional Hepatitis B Virus Genotype
一例硫胺素代谢功能障碍综合征5型患儿的临床特点及遗传学分析
中华医学遗传学杂志,1003-9406,2021-09-10.计算机模拟预测治疗性抗体聚集倾向性的进展及应用
中国医药工业杂志,1001-8255,2017.杆状病毒-昆虫细胞系统表达的戊型肝炎病毒衣壳蛋白p495的纯化、结构解析以及免疫原性分析
病毒学报,1000-8721,2016-05-15.人乳头瘤病毒16型感染上皮细胞过程的研究进展
病毒学报,1000-8721,2025-01-03.转录组测序技术研究进展
中国生化药物杂志,1005-1678,2017.抗HPV L1蛋白的广谱单克隆抗体或其抗原结合片段及它们的用途
CN103483447B,2015-11-25.