已发表成果:
WOK 论文 38 篇;中文核心 5 篇;其它论文 1 篇;专利发明 2 个;
Identification of (E)-1-((1H-indol-3-yl) methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77
The Ginsenoside Compound K Suppresses Stem-Cell-like Properties and Colorectal Cancer Metastasis by Targeting Hypoxia-Driven Nur77-Akt Feed-Forward Signaling
Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma
alpha-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXR alpha-AKT Signaling Pathway
Synthesis, SAR study, and bioactivity evaluation of a series of Quinoline-Indole-Schiff base derivatives: Compound 10E as a new Nur77 exporter and autophagic death inducer
Dapagliflozin: a sodium-glucose cotransporter 2 inhibitor, attenuates angiotensin II-induced cardiac fibrotic remodeling by regulating TGF beta 1/Smad signaling
Hypoxia-induced Nur77 activates PI3K/Akt signaling via suppression of Dicer/let-7i-5p to induce epithelial-to-mesenchymal transition
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators
Retinoid X receptor agonists attenuates cardiomyopathy in streptozotocin-induced type 1 diabetes through LKB1-dependent anti-fibrosis effects
The Roles of GSK-3 beta in Regulation of Retinoid Signaling and Sorafenib Treatment Response in Hepatocellular Carcinoma
Chemical Structures and Pharmacological Profiles of Ginseng Saponins
Hypoxia-induced Nur77 activates PI3K-p110a/Akt/mTOR via suppression of Dicer/let-7i-5p to induce epithelial-to-mesenchymal transition in colon cancer cells
Sialyl Lewis(x)-P-selectin cascade mediates tumor-mesothelial adhesion in ascitic fluid shear flow
Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma
TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells
Synthesis and biological evaluation of 1-(2-(adamantane-1-yl)-1H-indol-5-yl)-3-substituted urea/thiourea derivatives as anticancer agents
Quantification of protein copy number in single mitochondria: The Bcl-2 family proteins
Identification of Mitochondria-Targeting Anticancer Compounds by an in Vitro Strategy
Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells
Targeting Truncated Retinoid X Receptor-alpha by CF31 Induces TNF-alpha-Dependent Apoptosis
Regulation of proteolytic cleavage of retinoid X receptor-alpha by GSK-3 beta
RXR agonists inhibit high glucose-induced upregulation of inflammation by suppressing activation of the NADPH oxidase-nuclear factor-kappa B pathway in human endothelial cells
High-throughput multiparameter analysis of individual mitochondria
Nur77: a potential therapeutic target in cancer
Inhibition of beta-catenin signaling by nongenomic action of orphan nuclear receptor Nur77
Antagonist Effect of Triptolide on AKT Activation by Truncated Retinoid X Receptor-alpha
Regulation of Nur77 expression by beta-catenin and its mitogenic effect in colon cancer cells
NSAID Sulindac and Its Analog Bind RXR alpha and Inhibit RXR alpha-Dependent AKT Signaling
Oncogenic Potential of Retinoic Acid Receptor-gamma in Hepatocellular Carcinoma
A unique cytoplasmic localization of retinoic acid receptor-γ and its regulations
Cardenolides from Antiaris toxicaria as potent selective Nur77 modulators
苯胺嘧啶衍生物X-9通过下调整合素β1表达抑制肝细胞癌迁移侵袭
中国生物化学与分子生物学报,1007-7626,2019-12-31.小叶山葡萄化学成分及细胞毒活性研究
中国中药杂志,1001-5302,2015-08-01.视黄醇X受体激动剂蓓萨罗丁对自发性高血压大鼠心肌肥厚与心脏功能的影响和机制
中华高血压杂志,1673-7245,2014-11-15.Exfoliazone通过诱导细胞凋亡抑制HepG2细胞体外增殖
厦门大学学报(自然科学版),0438-0479,2010.大黄素诱导癌细胞凋亡和抑制视黄醇X受体的转录激活功能
药学学报,0513-4870,2008-04-12.过渡金属催化醇的空气/氧气氧化反应的研究进展
长江大学学报(自科版),1673-1409,2015-11-05.