PLCγ1 deficiency in chondrocytes accelerates the age-related changes in articular cartilage and subchondral bone

Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor a deficiency, associated with decreased ERK and Akt activation

RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype

Suppressing phosphoinositide-specific phospholipases C gamma 1 promotes mineralization of osteoarthritic subchondral bone osteoblasts via increasing autophagy, thereby ameliorating articular cartilage degeneration

Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium

Preventive but Not Therapeutic Topical Application of Local Anesthetics Can Inhibit Experimental Epidermolysis Bullosa Acquisita in Mice

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway

Suppressing PLC gamma 1 enhances osteogenic and chondrogenic potential of BMSCs

Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-kappa B pathway

Phosphoinositide specific phospholipase C gamma 1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Ubiquitin-specific peptidase 39 regulates the process of proliferation and migration of human ovarian cancer via p53/p21 pathway and EMT

IL-1 beta receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes

Chondroprotection of PPAR alpha activation by WY14643 via autophagy involving Akt and ERK in LPS-treated mouse chondrocytes and osteoarthritis model

TNF-alpha and IFN-gamma synergistically inhibit the repairing ability of mesenchymal stem cells on mice colitis and colon cancer

Different roles of Akt and mechanistic target of rapamycin in serum-dependent chondroprotection of human osteoarthritic chondrocytes

The inhibition of PLC gamma 1 protects chondrocytes against osteoarthritis, implicating its binding to Akt

Phosphoinositide-specific phospholipase C gamma 1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Antitumor activity of a Trans-thiosemicarbazone schiff base palladium (II) complex on human gastric adenocarcinoma cells

Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1

Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4 alpha and contributes to cell cycle control in hepatoma cells

Lentivirus-mediated PLC gamma 1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma

Involvement of Wnt/beta-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma

DAG/PKC delta and IP3/Ca2+/CaMK II beta Operate in Parallel to Each Other in PLC gamma 1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway

The Involvement of Mutual Inhibition of ERK and mTOR in PLC gamma 1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes

Protein kinase B and extracellular signal-regulated kinase contribute to the chondroprotective effect of morroniside on osteoarthritis chondrocytes

Matrine inhibits proliferation and induces apoptosis via BID-mediated mitochondrial pathway in esophageal cancer cells

Involvement of BID Translocation in Glycyrrhetinic Acid and 11-Deoxy Glycyrrhetinic Acid-Induced Attenuation of Gastric Cancer Growth

Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor

Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium- Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-kappa B Activation

Berberine ameliorates cartilage degeneration in interleukin-1 beta-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling

12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis

Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase C alpha in chondrocytes

17 beta-ESTRADIOL PROMOTES CELL PROLIFERATION IN RAT OSTEOARTHRITIS MODEL CHONDROCYTES VIA PI3K/AKT PATHWAY

Intestinal metabolite compound K of ginseng saponin potently attenuates metastatic growth of hepatocellular carcinoma by augmenting apoptosis via a bid-mediated mitochondrial pathway

12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase C alpha during gastric cancer cell apoptosis

The expression of protein kinase B in gastric cancer cell apoptosis induced by 12-O-tetradecanoylphorbol-1, 3-acetate