Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy

β₂-Microglobulin coaggregates with Aβ and contributes to amyloid pathology and cognitive deficits in Alzheimer's disease model mice

b2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function

Microglial Tmem59 Deficiency Impairs Phagocytosis of Synapse and Leads to Autism-Like Behaviors in Mice

USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and A beta generation

Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability

SNX14 deficiency-induced defective axonal mitochondrial transport in Purkinje cells underlies cerebellar ataxia and can be reversed by valproate

Trisomy 21-induced dysregulation of microglial homeostasis in Alzheimer's brains is mediated by USP25

Overexpression of Human SNX27 Enhances Learning and Memory Through Modulating Synaptic Plasticity in Mice

The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability