英文论文


文献类型
Review
题名
High-intensity focused ultrasound treatment for symptomatic uterine fibroids: a systematic review and meta-analysis
作者
Yan, Ling; Huang, Huimin; Lin, Jingwen; Yu, Ruimei
作者单位
[Yan, Ling; Huang, Huimin; Lin, Jingwen; Yu, Ruimei] Xiamen Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, 55 Zhenhai Rd, Xiamen 361000, Peoples R China.
通讯作者地址
Xiamen Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, 55 Zhenhai Rd, Xiamen 361000, Peoples R China.
Email
yanlingwork@163.com; 1348562877@qq.com
ResearchID
ORCID
期刊名称
INTERNATIONAL JOURNAL OF HYPERTHERMIA
出版社
TAYLOR & FRANCIS LTD
ISSN
0265-6736
出版信息
2022-12-31, 39 (1):230-238.
JCR
影响因子
ISBN
基金
会议名称
会议地点
会议开始日期
会议结束日期
关键词
High-intensity focused ultrasound treatment; symptomatic uterine fibroids; uterine artery embolization; traditional surgeries; meta-analysis
摘要
Objective This study was aimed at comparing the outcomes of high-intensity focused ultrasound (HIFU) with those of uterine artery embolization (UAE) and traditional surgeries for treating symptomatic uterine fibroids. Materials and methods We searched the following databases from their beginning to 5 November 2021: PubMed, Medline, Embase and Cochrane Library. Results Overall, 21 studies were included in this meta-analysis. The results revealed that HIFU had a higher re-intervention rate than UAE (relative risk [RR] = 4.06, 95% confidence interval [CI]: 2.47-6.69) and offered no significant advantages in reducing the symptom severity score (SSS) (mean difference [MD] = 17.01, 95% CI: 10.25-23.77) and improving the health-related quality of life (HRQoL) score (MD= -18.32, 95% CI: -24.87 to -11.78) in the treatment of symptomatic uterine fibroids. However, compared with UAE, HIFU may be associated with a higher pregnancy rate (RR = 17.44, 95% CI: 2.40-126.50) and may have a significant advantage in shortening pregnancy interval and preserving ovarian function. Moreover, upon comparing HIFU with traditional surgical treatments, the HIFU group showed significantly improved HRQoL score (MD = 2.25, 95% CI: 1.15-3.35), but the re-intervention rate (RR = 1.65, 95% CI: 0.59-4.57), pregnancy rate (RR = 1.01, 95% CI: 0.90-1.13), SSS and ovarian function did not significantly differ between the two groups. Conclusions Although HIFU has relatively high re-intervention rate, it may offer a higher pregnancy rate and shorter pregnancy interval with little influence on ovarian function, thus making it an attractive option for treating symptomatic fibroids in young women who wish to plan a pregnancy in the future.
一级学科
Oncology; Radiology, Nuclear Medicine & Medical Imaging
WOS入藏号
WOS:000748387900001
EI收录号
DOI
10.1080/02656736.2022.2029956
ESI
收录于
SCIE

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