Unveiling the Mechanisms of Apoptosis Induction by Deep-Sea-Derived Polyketide-Terpenoid Hybrids from <i>Penicillium allii-sativi</i>: A Focus on Mitochondrial and mTOR Pathways

Discovery of Sesquiterpene Lactones with Cytotoxicity from the Herb of <i>Youngia japonica</i>

Filicinic Acid Based Meroterpenoids with 6/6/6 Tricyclic Core from Hypericum Elodeoides and Their Anti-Alzheimer's Disease Effects

Discovery of sesquiterpene from Youngia japonica with antitumor effect

Four undescribed coumarin derivatives, with ten amides from the roots of Ficus hirta and their cytotoxic activities

Soil nutrients drive changes in the structure and functions of soil bacterial communities in a restored forest soil chronosequence

Four Undescribed Coumarins Derivatives, Along with Ten Amides from the Roots of Ficus Hirta and Their Cytotoxic Activities

Ergosterol Isolated from <i>Antrodia camphorata</i> Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice. <i>(</i>vol <i>28</i>,, 2406, 2023)

Apocarotenoids from<i> Equisetum</i><i> debile</i> Roxb. ex Vaucher regulate the lipid metabolism via the activation of the AMPK/ACC/SREBP-1c signaling pathway

Dysambiol, an Anti-inflammatory Secomeroterpenoid from a <i>Dysidea</i> sp. Marine Sponge

Apocarotenoids from Equisetum Debile Roxb. Ex Vaucher Regulate the Lipid Metabolism Via the Activation of the AMPK/ACC/SREBP-1c Signaling Pathway

Ergosterol Isolated from <i>Antrodia camphorata</i> Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice

Tautomeric phytosterols from Vernonia amygdalina Delile and their anti-cervical cancer activity

Seco-polyprenylated acylphloroglucinols from Hypericum elodeoides induced cell cycle arrest and apoptosis in MCF-7 cells via oxidative DNA damage

Bisabolane-type sesquiterpenes from <i>Vernonia amygdalina</i>: Absolute configuration and anti-inflammatory activity

Meroterpenthiazole A, a unique meroterpenoid from the deep-sea-derived Penicillium allii-sativi, significantly inhibited retinoid X receptor (RXR)-alpha transcriptional effect

Inhibitory effects of phenolic glycosides from Trollius chinensis Bunge on alpha-glucosidase: inhibition kinetics and mechanisms

Dysideanones F-G and dysiherbols D-E, unusual sesquiterpene quinones with rearranged skeletons from the marine sponge Dysidea avara

A natural product targets BRD4 to inhibit phase separation and gene transcription

Synthesis and Anti-Hepatoma Activities of U12 Derivatives Arresting G0/G1 Phase and Inducing Apoptosis by PI3K/AKT/mTOR Pathway

Two Resveratrol Oligomers Inhibit Cathepsin L Activity to Suppress SARS-CoV-2 Entry

A discussion on the affecting factors of the fitting procedures' reliability in isothermal titration calorimetry analysis

Phenolic glycosides and flavonoids with antioxidant and anticancer activities from Desmodium caudatum

Unprecedented Monoterpenoid Polyprenylated Acylphloroglucinols with a Rare 6/6/5/4 Tetracyclic Core, Enhanced MCF-7 Cells' Sensitivity to Camptothecin by Inhibiting the DNA Damage Response

Prenylated flavonoids from Ficus hirta induces HeLa cells apoptosis via MAPK and AKT signaling pathways

Discovery of andrastones from the deep-sea-derived Penicillium allii-sativi MCCC 3A00580 by OSMAC strategy

Jatrophane Diterpenoids from Euphorbia peplus as Multidrug Resistance Modulators with Inhibitory Effects on the ATR-Chk-1 Pathway

Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER alpha to inhibit RANKL signaling

A qualitative classification signature for post-surgery 5-fluorouracil-based adjuvant chemoradiotherapy in gastric cancer

Lignans and phenylpropanoids from the roots of Ficus hirta and their cytotoxic activities

Antiproliferative Sorbicillinoids From the Deep-Sea-Derived Penicillium allii-sativi

A new phenolic glycoside from Trollius chinensis Bunge with anti-inflammatory and antibacterial activities

Cytotoxic compound triacremoniate from Marine Fungus Acremonium citrinum. MMF4

Phakefustatins A-C: Kynurenine-Bearing Cycloheptapeptides as RXR alpha Modulators from the Marine Sponge Phakellia fusca

Chemical Constituents from Endophytic Fungus Annulohypoxylon cf. stygium in Leaves of Anoectochilus roxburghii

Identification of population-level differentially expressed genes in one-phenotype data

12-Deacetyl-12-epi-Scalaradial, a Scalarane Sesterterpenoid from a Marine Sponge Hippospongia sp., Induces HeLa Cells Apoptosis via MAPK/ERK Pathway and Modulates Nuclear Receptor Nur77

Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXR alpha transcriptional regulation

Phenolic Glycosides from the Roots of Ficus hirta Vahl. and Their Antineuroinflammatory Activities

Andrographolide promotes pancreatic duct cells differentiation into insulin-producing cells by targeting PDX-1

POLYPHENOLS FROM Polygonum cuspidatum REACTIVATE LATENT HIV

Hyperelodiones A-C, monoterpenoid polyprenylated acylphoroglucinols from Hypericum elodeoides, induce cancer cells apoptosis by targeting RXR alpha

Andrastone A From the Deep-Sea-Derived Fungus Penicillium allii-sativi Acts as an Inducer of Caspase and RXR alpha-Dependent Apoptosis

Cytotoxic Components from Hypericum elodeoides Targeting RXR alpha and Inducing HeLa Cell Apoptosis through Caspase-8 Activation and PARP Cleavage

Fuscasins A-D, Cycloheptapeptides from the Marine Sponge Phakellia fusca

Steroids from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475 Induced Apoptosis via Retinoid X Receptor (RXR)-alpha Pathway

Septosones A-C, in Vivo Anti-inflammatory Meroterpenoids with Rearranged Carbon Skeletons from the Marine Sponge Dysidea septosa

Stigmastane-type steroids with unique conjugated Delta(7,9(11)) diene and highly oxygenated side chains from the twigs of Vernonia amygdalina

Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice

Roquefortine J, a novel roquefortine alkaloid, from the deep-sea-derived fungus Penicillium granulatum MCCC 3A00475

Cytoskyrin C, an unusual asymmetric bisanthraquinone with cage-like skeleton from the endophytic fungus Diaporthe sp.

A New Xanthone from an Endophytic Fungus of Anoectochilus roxburghii

C-glycosides from the stems of Calophyllum membranaceum

Natural Compound Methyl Protodioscin Suppresses Proliferation and Inhibits Glycolysis in Pancreatic Cancer

Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells

Metabolism-Based Click-Mediated Platform for Specific Imaging and Quantification of Cell Surface Sialic Acids

Chiral separation and absolute configurations of two pairs of racemic polyprenylated benzophenones from Hypericum sampsonii

Norsampsone E, an unprecedented decarbonyl polycyclic polyprenylated acylphloroglucinol with a homoadamantyl core from: Hypericum sampsonii

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Quantification and semiquantification of multiple representative components for the holistic quality control of Allii Macrostemonis Bulbus by ultra high performance liquid chromatography with quadrupole time-of-flight tandem mass spectrometry

Study on chemical profiles and metabolites of Allii Macrostemonis Bulbus as well as its representative steroidal saponins in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Polyphenols isolated from leaves of Vitis thunbergii var. taiwaniana regulate APP related pathway

RXR alpha transcriptional inhibitors from the stems of Calophyllum membranaceum

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP

Cytotoxic metabolites from Botryotinia fuckeliana A-S-3: An endophytic fungus from Ajuga decumbens

Bioactive prenylated xanthones from the stems of Cratoxylum cochinchinense

Quantification and visualization of glutathione S-transferase omega 1 in cells using inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence microscopy

Novel polycyclic polyprenylated acylphloroglucinols from Hypericum sampsonii

Structure Elucidation and Biological Activity of Two New Trichothecenes from an Endophyte, Myrothecium roridum

Myrotheciumones: Bicyclic cytotoxic lactones isolated from an endophytic fungus of Ajuga decumbens

Total synthesis and RXR alpha-mediated transcription studies of neriifolone B and related compounds

Targeting Truncated Retinoid X Receptor-alpha by CF31 Induces TNF-alpha-Dependent Apoptosis

Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria

Integrin-targeted trifunctional probe for cancer cells: A 'seeing and counting' approach

Inhibition of Platelet Activation and Aggregation by Furostanol Saponins Isolated From the Bulbs of Allium macrostemon Bunge

Inhibition of beta-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

Europium-labeled activity-based probe through click chemistry: Absolute serine protease quantification using 153Eu isotope dilution ICP/MS

A resveratrol analog, phoyunbene B, induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells

Structural modification of ginsenoside Rh-2 by fatty acid esterification and its detoxification property in antitumor

Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2

Furocoumarin Derivatives from Radix Angelicae Dahuricae and Their Effects on RXR alpha Transcriptional Regulation

Three New Oblongolides from Phomopsis sp XZ-01, an Endophytic Fungus from Camptotheca acuminate

Xanthone and Benzophenone Glycosides from the Stems of Cratoxylum formosum ssp pruniflorum

A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2

New Steroidal Glycosides Isolated as CD40L Inhibitors of Activated Platelets

Bioactive Xanthones from the Stems of Cratoxylum formosum ssp pruniflorum

Two New Steroidal Saponins from Allium macrostemon Bunge and Their Cytotoxity on Different Cancer Cell Lines

Four new biflavonoids from Selaginella uncinata and their anti-anoxic effect