学者信息

E674Q (Shanghai APP mutant), a novel amyloid precursor protein mutation, in familial late-onset Alzheimer's disease

GENES & DISEASES,2352-4820,2024-03.
Zhang, Yongfang; Xie, Xinyi; Chen, Boyu; Pan, Lina; Li, Jianping; Wang, Wanbing; Wang, Jintao; Tang...
WOS:001072977500001 10.1016/j.gendis.2023.02.051
收录情况：SCIE

TREMendous microglial effects on neurons

IMMUNITY,1074-7613,2024-01-09.
Chen, Xiao-Fen; Bu, Guojun
WOS:001156815200001 10.1016/j.immuni.2023.12.007
收录情况：SCIE

Human ApoE2 protects mice against <i>Plasmodium berghei</i> ANKA experimental cerebral malaria

MBIO,2150-7511,2023-12-19.
Liang, Rui; Rao, Hengjun; Pang, Qin; Xu, Ruixue; Jiao, Zhiwei; Lin, Lirong; Li, Li; Zhong, Li; Zhan...
WOS:001142727700079 10.1128/mbio.02346-23
收录情况：SCIE

Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer's disease model by restoring BDNF signaling

BRAIN BEHAVIOR AND IMMUNITY,0889-1591,2023-10.
Wang, Wanbing; Li, Yanzhong; Ma, Fangling; Sheng, Xuan; Chen, Kai; Zhuo, Rengong; Wang, Chen; Zheng...
WOS:001047422000001 10.1016/j.bbi.2023.07.011
收录情况：SCIE

Identification of the minimal active soluble TREM2 sequence for modulating microglial phenotypes and amyloid pathology

JOURNAL OF NEUROINFLAMMATION,,2021-12-10.
Sheng, Xuan; Yao, Yunling; Huang, Ruizhi; Xu, Ying; Zhu, Yifei; Chen, Linting; Zhang, Lianshuai; Wa...
WOS:000729095600002 10.1186/s12974-021-02340-7
收录情况：SCIE

TMEM59 interacts with TREM2 and modulates TREM2-dependent microglial activities

CELL DEATH & DISEASE,2041-4889,2020-08-13.
Liu, Zhaoji; Ning, Jinhuan; Zheng, Xiaoyuan; Meng, Jian; Han, Linkun; Zheng, Honghua; Zhong, Li; Ch...
WOS:000568776500002 10.1038/s41419-020-02874-3
收录情况：SCIE

The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer's Disease

FRONTIERS IN AGING NEUROSCIENCE,1663-4365,2019-11-26.
Zhong, L; Chen, XF
WOS:000501863600001 10.3389/fnagi.2019.00328
收录情况：SCIE

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model (vol 10, 1365, 2019)

NATURE COMMUNICATIONS,2041-1723,2019-07-02.
Zhong, L; Xu, Y; Zhuo, RG; Wang, TT; Wang, K; Huang, RZ; Wang, DX; Gao, Y; Zhu, YF; Sheng, X; Chen,...
WOS:000473426600001 10.1038/s41467-019-10950-2
收录情况：SCIE

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model

NATURE COMMUNICATIONS,2041-1723,2019-03-25.
Zhong, L; Xu, Y; Zhuo, RG; Wang, TT; Wang, K; Huang, RZ; Wang, DX; Gao, Y; Zhu, YF; Sheng, X; Chen,...
WOS:000462142200008 10.1038/s41467-019-09118-9
收录情况：SCIE

TREM2 in Alzheimer's Disease: Microglial Survival and Energy Metabolism

FRONTIERS IN AGING NEUROSCIENCE,1663-4365,2018-11-23.
Zheng, HH; Cheng, BY; Li, YF; Li, X; Chen, XF; Zhang, YW
WOS:000451095500001 10.3389/fnagi.2018.00395
收录情况：SCIE

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

MOLECULAR NEURODEGENERATION,1750-1326,2018-03-27.
Zhong, Li; Wang, Zongqi; Wang, Daxin; Wang, Zhe; Martens, Yuka A.; Wu, Linbei; Xu, Ying; Wang, Kai;...
WOS:000428939400001 10.1186/s13024-018-0247-7
收录情况：SCIE

TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway

FRONTIERS IN AGING NEUROSCIENCE,1663-4365,2017-06-21.
Zhong, Li; Zhang, Zhen-Lian; Li, Xinxiu; Liao, Chunyan; Mou, Pengfei; Wang, Tingting; Wang, Zongqi;...
WOS:000403770600001 10.3389/fnagi.2017.00204
收录情况：SCIE

Soluble TREM2 induces inflammatory responses and enhances microglial survival

JOURNAL OF EXPERIMENTAL MEDICINE,0022-1007,2017-03.
Zhong, Li; Chen, Xiao-Fen; Wang, Tingting; Wang, Zhe; Liao, Chunyan; Wang, Zongqi; Huang, Ruizhi; W...
WOS:000395828600003 10.1084/jem.20160844
收录情况：SCIE

TREM2 Promotes Microglial Survival by Activating Wnt/beta-Catenin Pathway

JOURNAL OF NEUROSCIENCE,0270-6474,2017-02-15.
Zheng, Honghua; Jia, Lin; Liu, Chia-Chen; Rong, Zhouyi; Zhong, Li; Yang, Longyu; Chen, Xiao-Fen; Fr...
WOS:000394431100011 10.1523/JNEUROSCI.2459-16.2017
收录情况：SCIE

LRP1 modulates the microglial immune response via regulation of JNK and NF-kappa B signaling pathways

JOURNAL OF NEUROINFLAMMATION,1742-2094,2016-12-08.
Yang, Longyu; Liu, Chia-Chen; Zheng, Honghua; Kanekiyo, Takahisa; Atagi, Yuka; Jia, Lin; Wang, Daxi...
WOS:000390715100001 10.1186/s12974-016-0772-7
收录情况：SCIE

TREMs in Alzheimer's disease: Genetic and clinical investigations

CLINICA CHIMICA ACTA,0009-8981,2016-12-01.
Cheng, Jia; Guo, XiaoFeng; Zhang, Tian; Zhong, Li; Bu, GuoJun; Chen, XiaoFen
WOS:000390726500017 10.1016/j.cca.2016.10.022
收录情况：SCIE

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

NEUROBIOLOGY OF AGING,0197-4580,2016-06.
Zheng, Honghua; Liu, Chia-Chen; Atagi, Yuka; Chen, Xiao-Fen; Jia, Lin; Yang, Longyu; He, Wencan; Zh...
WOS:000375129500015 10.1016/j.neurobiolaging.2016.03.004
收录情况：SCIE

Apolipoprotein E epsilon 2 allele and low serum cholesterol as risk factors for gastric cancer in a Chinese Han population

SCIENTIFIC REPORTS,2045-2322,2016-01-28.
Kang, Ranran; Li, Ping; Wang, Tingting; Li, Xinxiu; Wei, Zichen; Zhang, Zhenlian; Zhong, Li; Cao, L...
WOS:000368781300001 10.1038/srep19930
收录情况：SCIE

A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism

MOLECULAR NEURODEGENERATION,1750-1326,2016-01-10.
Zhong, Li; Xie, Yong-Zhuang; Cao, Tian-Tian; Wang, Zongqi; Wang, Tingting; Li, Xinxiu; Shen, Rui-Ch...
WOS:000367911000001 10.1186/s13024-016-0069-4
收录情况：SCIE

Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students

PLOS ONE,1932-6203,2015-11-17.
Chen, Xiao-Fen; Wei, Zichen; Wang, Tingting; Zhang, Zhen-Lian; Wang, Yiwei; Heckman, Michael G.; Di...
WOS:000365153400048 10.1371/journal.pone.0143157
收录情况：SCIE、SSCI

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

JOURNAL OF BIOLOGICAL CHEMISTRY,0021-9258,2015-10-23.
Atagi, Yuka; Liu, Chia-Chen; Painter, Meghan M.; Chen, Xiao-Fen; Verbeeck, Christophe; Zheng, Hongh...
WOS:000363527300025 EI:20154401452672 10.1074/jbc.M115.679043
收录情况：SCIE、EI

Transcriptional regulation and its misregulation in Alzheimer's disease

MOLECULAR BRAIN,1756-6606,2013-10-21.
Chen, Xiao-Fen; Zhang, Yun-wu; Xu, Huaxi; Bu, Guojun
WOS:000328839800001 10.1186/1756-6606-6-44
收录情况：SCIE

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