Tpgen: a language model for stable protein design with a specific topology structure

Sequence-specific nanoparticle barcode strategy for multiplex human enterovirus typing

System design and clinical validation of intelligent nucleic acid POCT for un SARS-CoV-2 detection within 30 min

Orchestrated Codelivery of Peptide Antigen and Adjuvant to Antigen-Presenting Cells by Using an Engineered Chimeric Peptide Enhances Antitumor T-Cell Immunity

Wa-VP4*as a candidate rotavirus vaccine induced homologous and heterologous virus neutralizing antibody responses in mice, pigs, and cynomolgus monkeys

An Inhibitor-Monitorable Single-Tube Duplex Quantitative Real-Time PCR Assay for the Detection of '<i>Candidatus</i> Liberibacter asiaticus'

Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects

A non-viral DNA delivery system consisting of multifunctional chimeric peptide fused with zinc-finger protein

Design of a recombinant asparaginyl ligase for site-specific modification using efficient recognition and nucleophile motifs

Long-term efficacy of a recombinant hepatitis E vaccine in adults: 10-year results from a randomised, double-blind, placebo-controlled, phase 3 trial

Roots applicable, high sensitivity and specificity assay for the detection of<i> Candidatus</i> Liberibacter asiaticus in<i> citrus</i> roots and fruits

Numerical and experimental investigation on the performance of rapid ultrasonic-assisted nucleic acid extraction based on dispersive two-phase flow

Empirical validation of ProteinMPNN's efficiency in enhancing protein fitness

SurfPro-NN: A 3D point cloud neural network for the scoring of protein-protein docking models based on surfaces features and protein language models

Design and Optimization of Ultrasound-Assisted Nucleic Acid Extraction System

System Design and Clinical Validation of Intelligent Nucleic Acid POCT for Ultra-High Sensitivity SARS-CoV-2 Detection within 30 Min

Reconsideration of Maternal Serological Testing for Predicting Congenital CMV Infection

All-in-one microfluidic chip for 30-min quantitative point-of-care-testing of nucleic acids

Anti-Epstein-Barr Virus BNLF2b for Mass Screening for Nasopharyngeal Cancer

Nanoparticle-based multivalent human antibodies offer potent and broad neutralization against Omicron sublineages

Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters

Sophisticated and precise: design and implementation of a real-time optical detection system for ultra-fast PCR

Hepatitis B Core Antibody Level: A Surrogate Marker for Host Antiviral Immunity in Chronic Hepatitis B Virus Infections

Ultra-fast, sensitive and low-cost real-time PCR system for nucleic acid detection

Bacterial-Artificial-Chromosome-Based Genome Editing Methods and the Applications in Herpesvirus Research

Ultrafast Microfluidic PCR Thermocycler for Nucleic Acid Amplification

All-in-One Microfluidic Chip for the Point-of-Care-Testing of Nucleic Acids: Combining a Dynamic-Seal Microvalve, Ultrasound-Assisted Reaction Chamber, and Slice Amplification with a Fluorescence Detection System

PointDE: Protein Docking Evaluation Using 3D Point Cloud Neural Network

Nasal irrigation efficiently attenuates SARS-CoV-2 Omicron infection, transmission and lung injury in the Syrian hamster model

The duration and breadth of antibody responses to 3-dose of inactivated COVID-19 vaccinations in healthy blood donors: An observational study

Generation and characterization of mouse monoclonal antibodies against the VP4 protein of group A human rotaviruses

Bivalent rotavirus VP4* stimulates protective antibodies against common genotypes of human rotaviruses

Biomarkers of interstitial lung disease associated with primary Sjogren's syndrome

Infection, pathology and interferon treatment of the SARS-CoV-2 Omicron BA.1 variant in juvenile, adult and aged Syrian hamsters

New discovery of high-affinity SARS-CoV-2 spike S2 protein binding peptide selected by PhIP-Seq

Serum MUC5AC protein levels are correlated with the development and severity of connective tissue disease-associated pulmonary interstitial lesions

An Integrated, Real-Time Convective PCR System for Isolation, Amplification, and Detection of Nucleic Acids

Predictors of long-term prognosis in rheumatoid arthritis-related interstitial lung disease

Development of a fluorescent probe hydrolysis-insulated isothermal PCR for rapid and sensitive on-site detection of African swine fever virus

A genetic engineering strategy for editing near-infrared-II fluorophores

An encodable multiplex microsphere-phase amplification sensing platform detects SARS-CoV-2 mutations

A hand-held, real-time, AI-assisted capillary convection PCR system for point-of-care diagnosis of African swine fever virus

Whole blood GBP5 protein levels in patients with and without active tuberculosis

Characterization of Monoclonal Antibodies Recognizing Citrulline-Modified Residues

Pre-existing maternal IgG antibodies as a protective factor against congenital cytomegalovirus infection: A mother-child prospective cohort study

Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production

Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19

AI-Assisted Analysis to HIV Lateral Flow Test with a Hybrid Model Running on a Distributed Diagnosis System

Transferable, easy-to-use and room-temperature-storable PCR mixes for microfluidic molecular diagnostics

Numerical and Experimental Investigation of Liquid Residue in 90 degrees Bend Microchannel Based on Gas-Liquid Two-Phase Flow

Rapid PCR powered by microfluidics: A quick review under the background of COVID-19 pandemic

Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo

Asymptomatic and Symptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in Close Contacts of Coronavirus Disease 2019 (COVID-19) Patients: A Seroepidemiological Study

Sporadic hand, foot, and mouth disease cases associated with non-C4 enterovirus 71 strains in Xiamen, China, from 2009 to 2018

Elimination of human cytomegalovirus DNA degradation in urine

Accurate nucleic acid quantification in a single sample tube without the need for calibration

Comparison of detection strategies for screening and confirming congenital cytomegalovirus infection in newborns in a highly seroprevalent population: a mother-child cohort study

Methylation of CYP1A1 and VKORC1 promoter associated with stable dosage of warfarin in Chinese patients

A Novel Clustering Method Using Variational Autoencoder with Reliable Sample Decision and Balanced K-Means++ for Single-particle Cryo-EM Images

Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster

Several FDA-Approved Drugs Effectively Inhibit SARS-CoV-2 Infection in vitro

Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors

Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection

Maternal CMV seroprevalence rate in early gestation and congenital cytomegalovirus infection in a Chinese population

Machine Learning for Structure Determination in Single-Particle Cryo-Electron Microscopy: A Systematic Review

Development of amplification system for point-of-care test of nucleic acid

Seroconversion Rate and Diagnostic Accuracy of Serological Tests for Coronavirus 2019 Reply

A novel point-of-care test of respiratory syncytial viral RNA based on cellulose-based purification and convective PCR

Molecular characterization of an uncommon multigene Reassortant G1P[4] rotavirus identified in China

Virus shedding dynamics in asymptomatic and mildly symptomatic patients infected with SARS-CoV-2

Plasma miRNA profiles associated with stable warfarin dosage in Chinese patients

A plasma separator with a multifunctional deformable chamber equipped with a porous membrane for point-of-care diagnostics

Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks

Heat inactivation decreases the qualitative real-time RT-PCR detection rates of clinical samples with high cycle threshold values in COVID-19

Serology characteristics of SARS-CoV-2 infection after exposure and post-symptom onset

An immunoassay cassette with a handheld reader for HIV urine testing in point-of-care diagnostics

High-Efficiency Plasma Separator Based on Immunocapture and Filtration

A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice

Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells

Free convective PCR: From principle study to commercial applications-A critical review

Room-temperature-storable PCR mixes for SARS-CoV-2 detection

Nucleic Acid Testing for Coronavirus Disease 2019: Demand, Research Progression, and Perspective

Incidence and mortality of nasopharyngeal carcinoma: interim analysis of a cluster randomized controlled screening trial (PRO-NPC-001) in southern China

Molecular epidemiology of group A rotavirus in outpatient diarrhea infants and children in Chongqing, China, 2011-2015

Transcriptional response of USP18 predicts treatment outcomes of interferon-alpha in HBeAg-positive chronic hepatitis B patientsefere

An efficient isothermal PCR method for on-site detection of nucleic acid

The distinct impact of maternal antibodies on the immunogenicity of live and recombinant rotavirus vaccines

An effector from cotton bollworm oral secretion impairs host plant defense signaling

PSO+: nonlinear fitting fluorescence data based on particle swarm optimizing combine with other iteration algorithm

Intermittent abortive reactivation of Epstein-Barr virus during the progression of nasopharyngeal cancer as indicated by elevated antibody levels

A point of care platform based on microfluidic chip for nucleic acid extraction in less than 1 minute

Real-time capillary convective PCR based on horizontal thermal convection

An HRP-labeled lateral flow immunoassay for rapid simultaneous detection and differentiation of influenza A and B viruses

An automated microfluidic chemiluminescence immunoassay platform for quantitative detection of biomarkers

Development of multiplex real-time reverse-transcriptase polymerase chain reaction assay for simultaneous detection of Zika, dengue, yellow fever, and chikungunya viruses in a single tube

Adiponectin is valuable in the diagnosis of acute heart failure with renal insufficiency

Autoreactive T cells to citrullinated HSP90 are associated with interstitial lung disease in rheumatoid arthritis

Development and evaluation of a rapid point-of-care test for detecting the hepatitis E virus antigen

An emerging and expanding Glade accounts for the persistent outbreak of Coxsackievirus A6-associated hand, foot, and mouth disease in China since 2013

Nonnegative matrix factorization with Hessian regularizer

Expression and characterization of a novel truncated rotavirus VP4 for the development of a recombinant rotavirus vaccine

Cytomegalovirus Shedding in Healthy Seropositive Female College Students: A 6-Month Longitudinal Study

IL-6 release of Rv0183 antigen-stimulated whole blood is a potential biomarker for active tuberculosis patients

A Single-Bead-Based, Fully Integrated Microfluidic System for High-Throughput CD4+T Lymphocyte Enumeration

Establishment and validation of a two-step screening scheme for improved performance of serological screening of nasopharyngeal carcinoma

A Rapid On-Site Assay for the Detection of Influenza A by Capillary Convective PCR

A low cost, membranes based serum separator modular

Rapid enumeration of CD4 + T lymphocytes using an integrated microfluidic system based on Chemiluminescence image detection at point-of-care testing

Evaluation of a newly developed chemiluminescence immunoassay for detecting cardiac troponin T

Serological survey of neutralizing antibodies to eight major enteroviruses among healthy population

Using MOEA with Redistribution and Consensus Branches to Infer Phylogenies

Multiplex analysis of plasma cytokines/chemokines showing different immune responses in active TB patients, latent TB infection and healthy participants

Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin

A bead-based microfluidic system for joint detection in TORCH screening at point-of-care testing

Severe hand, foot and mouth disease associated with Coxsackievirus A10 infections in Xiamen, China in 2015

Epidemics and aetiology of hand, foot and mouth disease in Xiamen, China, from 2008 to 2015

AUTOREACTIVE T CELLS TO CITRULLINATED HSP90 IN INTERSTITIAL LUNG DISEASE IN RHEUMATOID ARTHRITIS

Instrument-free point-of-care molecular diagnosis of H1N1 based on microfluidic convective PCR

Baseline antibody level may help predict the risk of active human cytomegalovirus infection in a HCMV seropositive population

The prevalence of latent tuberculosis infection in rural Jiangsu, China

A Smartphone-Based Genotyping Method for Hepatitis B Virus at Point-of-Care Settings

A paper-based microfluidic Dot-ELISA system with smartphone for the detection of influenza A

Characterization and analysis of real-time capillary convective PCR toward commercialization

A Low-Cost and Fast Real-Time PCR System Based on Capillary Convection

Establishment and validation of an enzyme-linked immunosorbent assay for IgG antibody against cytomegalovirus based on pp150 antigen

Rare RET Variant p.D707E in a Chinese Pedigree with Hereditary Medullary Thyroid Carcinoma

Using a Machine-Learning Approach to Predict Discontinuous Antibody-Specific B-Cell Epitopes

Microfluidic Chips for Cell Capturing and Separation

Enzyme-free colorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and 4-MBA-MA-AgNPs

A highly specific rapid antigen detection assay for on-site diagnosis of MERS

A fast and low-cost genotyping method for hepatitis B virus based on pattern recognition in point-of-care settings

A smartphone-based point-of-care diagnosis of H1N1 with microfluidic convection PCR

Development and evaluation of rapid point-of-care tests for detection of Enterovirus 71 and Coxsackievirus A16 specific immunoglublin M antibodies

Epidemiologic and Etiologic Characteristics of Hand, Foot, and Mouth Disease in Chongqing, China Between 2010 and 2013

Development of a quantifiable optical reader for lateral flow immunoassay

Evaluation of a novel chemiluminescent microplate enzyme immunoassay for hepatitis B surface antigen detection

Immunogenicity and protective efficacy of rotavirus VP8*fused to cholera toxin B subunit in a mouse model

Virus-mimetic nanovesicles as a versatile antigen-delivery system

5-year prospective cluster randomised controlled study of a new nasopharyngeal carcinoma screening programme

Target cells capture and detection based on a surface plasmon resonance biosensor

CD4+T Lymphocyte Counting Technologies Based on Microfluidic Chip

Rapid fluorescent lateral-flow immunoassay for hepatitis B virus genotyping

Scanning-fluorescence reader based on embedded system

Point-of-care test for C-reactive protein by a fluorescence-based lateral flow immunoassay

A Convenient Nucleic Acid Test on the Basis of the Capillary Convective PCR for the On-Site Detection of Enterovirus 71

Improved characteristics and protective efficacy in an animal model of E-coli-derived recombinant double-layered rotavirus virus-like particles

Acetylcholinesterase-catalyzed hydrolysis allows ultrasensitive detection of pathogens with the naked eye

Specific primer amplification of the VP1 region directed by 5 ' UTR sequence analysis: Enterovirus testing and identification in clinical samples from hand-foot-and-mouth disease patients

Serum miR-483-5p as a potential biomarker to detect hepatocellular carcinoma

A one-step dipstick assay for the on-site detection of nucleic acid

Hepatitis B Virus Surface Antigen (HBsAg)-Positive and HBsAg-Negative Hepatitis B Virus Infection among Mother-Teenager Pairs 13 Years after Neonatal Hepatitis B Virus Vaccination

An assessment of hepatitis E virus (HEV) in US blood donors and recipients: no detectable HEV RNA in 1939 donors tested and no evidence for HEV transmission to 362 prospectively followed recipients

Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors

Evaluation of human enterovirus 71 and coxsackievirus A16 specific immunoglobulin M antibodies for diagnosis of hand-foot-and-mouth disease

Differential diagnosis of pandemic (H1N1) 2009 infection by detection of haemagglutinin with an enzyme-linked immunoassay

A rapid test for the detection of influenza A virus including pandemic influenza A/H1N1 2009

Performance of Detecting IgM Antibodies against Enterovirus 71 for Early Diagnosis

Novel Double-Antigen Sandwich Immunoassay for Human Hepatitis B Core Antibody

Molecular and Phylogenetic Analyses Suggest an Additional Hepatitis B Virus Genotype