TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation

An Integrated Multi-Omics Analysis Identifying Immune Subtypes of Pancreatic Cancer

Exo70 Promotes the Invasion of Pancreatic Cancer Cells via the Regulation of Exosomes

Trends and projections of inflammatory bowel disease at the global, regional and national levels, 1990-2050: a bayesian age-period-cohort modeling study

Identification of m6A-associated LncRNAs as predict factors for the immune infiltration and prognosis of thyroid cancer

Single-cell landscape of immune cells during the progression from HBV infection to HBV cirrhosis and HBV-associated hepatocellular carcinoma

Single-cell landscape of immune cells in human livers affected by HBV-related cirrhosis

An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration

The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma

Berplatin: A Conjugate of Berberine and Cisplatin Serving as a Potent Antitumor Agent with Distinctive Tumor Cell Uptake and Minimal Side Effects

SINGLE-CELL LANDSCAPE OF IMMUNE CELLS IN HEALTHY AND HEPATITIS B CIRRHOTIC HUMAN LIVER

Studies of the Efficacy of Low-Dose Apatinib Monotherapy as Third-Line Treatment in Patients with Metastatic Colorectal Cancer and Apatinib's Novel Anticancer Effect by Inhibiting Tumor-Derived Exosome Secretion

Gap junctions mediate glucose transfer to promote colon cancer growth in three-dimensional spheroid culture

LIMK2 Is a Novel Prognostic Biomarker and Correlates With Tumor Immune Cell Infiltration in Lung Squamous Cell Carcinoma

The HNF4 alpha-BC200-FMR1-Positive Feedback Loop Promotes Growth and Metastasis in Invasive Mucinous

Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers

Deregulation of Exo70 Facilitates Innate and Acquired Cisplatin Resistance in Epithelial Ovarian Cancer by Promoting Cisplatin Efflux

Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway

Merging C-H Vinylation with Switchable 6 pi-Electrocyclizations for Divergent Heterocycle Synthesis

Structure-Activity Relationship Study Enables the Discovery of a Novel Berberine Analogue as the RXR alpha Activator to Inhibit Colon Cancer

Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-kappa B pathway

ULK1 phosphorylates Exo70 to suppress breast cancer metastasis

Phosphoinositide specific phospholipase C gamma 1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1 alpha

Ubiquitin-specific peptidase 39 regulates the process of proliferation and migration of human ovarian cancer via p53/p21 pathway and EMT

B-125, a novel berberine derivative, acts as a better retinoid X receptor a agonist with stronger anti-tumor activity in colon cancer

TNF-alpha and IFN-gamma synergistically inhibit the repairing ability of mesenchymal stem cells on mice colitis and colon cancer

Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer

High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer

Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy

Berberine binds RXR alpha to suppress beta-catenin signaling in colon cancer cells

Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth

Phosphoinositide-specific phospholipase C gamma 1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Exo70 is an independent prognostic factor in colon cancer

Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-beta signaling pathway

Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4 alpha and contributes to cell cycle control in hepatoma cells

Lentivirus-mediated PLC gamma 1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma

Seed Oil of Brucea javanicaInduces Cell Cycle Arrest and Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction in Human Lung Cancer Cells

Involvement of Wnt/beta-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma

Protecting-Group-Free Total Synthesis of (-)-Jiadifenolide: Development of a [4+1] Annulation toward Multisubstituted Tetrahydrofurans

Matrine inhibits proliferation and induces apoptosis via BID-mediated mitochondrial pathway in esophageal cancer cells

Involvement of BID Translocation in Glycyrrhetinic Acid and 11-Deoxy Glycyrrhetinic Acid-Induced Attenuation of Gastric Cancer Growth

Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor

Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium- Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-kappa B Activation

Berberine ameliorates cartilage degeneration in interleukin-1 beta-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling

Chemopreventive effects of berberine on intestinal tumor development in Apc(min/+) mice

Berberine Inhibits Proliferation and Down-Regulates Epidermal Growth Factor Receptor through Activation of Cbl in Colon Tumor Cells

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

HBsAg Inhibits the Translocation of JTB into Mitochondria in HepG2 Cells and Potentially Plays a Role in HCC Progression

Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway

p53 Facilitates BH3-only BID nuclear export to induce apoptosis in the irrepairable DNA damage response

Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst

Intestinal metabolite compound K of ginseng saponin potently attenuates metastatic growth of hepatocellular carcinoma by augmenting apoptosis via a bid-mediated mitochondrial pathway

Convergence between Wnt-beta-catenin and EGFR signaling in cancer

Bid Stands at the Crossroad of Stress-Response Pathways

Myristoylated Naked2 antagonizes Wnt-β-catenin activity by degrading dishevelled-1 at the plasma membrane

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1 alpha up-regulation and MMP9 activation