已发表成果:
WOK 论文 5 篇;
Metabolic stress induces a double-positive feedback loop between AMPK and SQSTM1/p62 conferring dual activation of AMPK and NFE2L2/NRF2 to synergize antioxidant defense
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer