已发表成果:
WOK 论文 79 篇;中文核心 3 篇;其它论文 14 篇;专利发明 3 个;
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex
Identification of serum metabolites enhancing inflammatory responses in COVID-19
Low-dose metformin targets the lysosomal AMPK pathway through PEN2
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1
Aldolase deployed for surveilling glucose
Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control
Glucose Starvation Blocks Translation at Multiple Levels
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress
Carbohydrates: Not All that Bad?
Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
Methods to Study Lysosomal AMPK Activation
Metformin Activates AMPK through the Lysosomal Pathway
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy
A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
RHOBTB3 promotes proteasomal degradation of HIF alpha through facilitating hydroxylation and suppresses the Warburg effect
AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation
Mechanism and Physiological Significance of Growth Factor-Related Autophagy
The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense
PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy
The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling
GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy
Revealing a steroid receptor ligand as a unique PPAR gamma agonist
Cdk5-Mediated Phosphorylation of Axin Directs Axon Formation during Cerebral Cortex Development
Molecular Basis of Wnt Activation via the DIX Domain Protein Ccd1
AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation
ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers
Axin determines cell fate by controlling the p53 activation threshold after DNA damage
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Rock2 controls TGF beta signaling and inhibits mesoderm induction in zebrafish embryos
Cytosporone B is an agonist for nuclear orphan receptor Nur77
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice
Determinants that control the distinct subcellular localization of p38-PRAK and p38-PRAK complexes
CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5
Regulation of Cidea protein stability by the ubiquitin-mediated proteasomal degradation pathway
Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins
Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death
p53 mediates the negative regulation of MDM2 by orphan receptor TR3
Determinants that control the specific interactions between TAB1 and p38 alpha
Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia
Frequency and distribution of AP-1 sites in the human genome
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation
Axin: A master scaffold for multiple signaling pathways
Detection of point mutations of the Axin1 gene in colorectal cancers
Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation
单磷酸腺苷激活的蛋白激酶(AMPK)调控机制的研究进展
厦门大学学报(自然科学版),0438-0479,2018.凡纳滨对虾G蛋白Gα_q基因的克隆和功能鉴定
海洋科学,1000-3096,2008-08-09.凡纳滨对虾G蛋白Gα_s基因的克隆和功能鉴定
厦门大学学报(自然科学版),0438-0479,2006-05-30.AMPK:不仅能感应细胞的能量状态还能感应葡萄糖
科学新闻,1671-6582,2019-04-25.AIDA通过内质网相关的蛋白质降解途径选择性下调脂肪合成途径的代谢酶从而减缓肠道脂肪吸收并防止肥胖发生
科学新闻,1671-6582,2019-04-25.生物科学本科教学质量保障监控体系的构建与探索
高校生物学教学研究(电子版),2095-1574,2018.肿瘤代谢异常的关键蛋白质作用机制及其分子调控网络
中国科技成果,1009-5659,2018.葡萄糖感应器及其AMPK活性和细胞代谢状态的调控机理
前沿科学,1673-8128,2018.ULK1/2所构成的信号节点除控制细胞自噬外还控制葡萄糖代谢通路
科学新闻,1671-6582,2017.遵循人才培养规律的生物科学专业课程体系建设探讨
高校生物学教学研究(电子版),2095-1574,2016-09-15.细胞能量代谢稳态的调控
中国基础科学,1009-2412,2014-06-15.内外源性p53诱导大鼠胶质瘤细胞C6 RGS16蛋白的表达
现代肿瘤医学,1672-4992,2008-05-25.凡纳滨对虾G蛋白Gβ_1亚基的克隆、表达与鉴定
海洋水产研究,1000-7075,2006-06-30.Axin基因的表达对神经胶质瘤细胞系C6生物学特性的影响
现代肿瘤医学,1672-4992,2006-05-25.外源性RGS16基因稳定转染对胶质瘤C6细胞生长的影响
癌症,1000-467X,2006-01-05.真核表达载体pIRES2-EGFP-Axin的构建及其在神经胶质瘤细胞内的表达
细胞与分子免疫学杂志,1007-8738,2005-07-18.胶质瘤中Axin基因点突变检测及表达研究
中华神经外科疾病研究杂志,1671-2897,2003-10-30.2-[(2, 3, 4-三烷氧基-6-酰基)苯基]乙酸酯及其制备方法与应用
CN101891618B,2012-10-31.