AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

HuR promotes triglyceride synthesis and intestinal fat absorption

Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance

BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes

Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Low-dose metformin targets the lysosomal AMPK pathway through PEN2

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy

Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

Carbohydrates: Not All that Bad?

Knockout of ULK1/2 protects against acetaminophen-induced acute liver injury independent of autophagy? Reply

Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate

AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

Metformin Activates AMPK through the Lysosomal Pathway

C-terminus of MUC16 activates Wnt signaling pathway through its interaction with beta-catenin to promote tumorigenesis and metastasis

ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy

RHOBTB3 promotes proteasomal degradation of HIF alpha through facilitating hydroxylation and suppresses the Warburg effect

The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin

Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24

AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation

Periostin Contributes to the Acquisition of Multipotent Stem Cell-Like Properties in Human Mammary Epithelial Cells and Breast Cancer Cells

MDM2 Inhibits Axin-Induced p53 Activation Independently of Its E3 Ligase Activity

Mechanism and Physiological Significance of Growth Factor-Related Autophagy

PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation

Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy

The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

Revealing a steroid receptor ligand as a unique PPAR gamma agonist

Identification of Novel SNPs by Next-Generation Sequencing of the Genomic Region Containing the APC Gene in Colorectal Cancer Patients in China

Axin determines cell fate by controlling the p53 activation threshold after DNA damage

Asymmetric syntheses and Wnt signal inhibitory activity of melleumin A and four analogues of melleumins A and B