Unveiling the Mechanisms of Apoptosis Induction by Deep-Sea-Derived Polyketide-Terpenoid Hybrids from <i>Penicillium allii-sativi</i>: A Focus on Mitochondrial and mTOR Pathways

Penicopeptide A (PPA) from the deep-sea-derived fungus promotes osteoblast-mediated bone formation and alleviates ovariectomy-induced bone loss by activating the AKT/GSK-3β/β-catenin signaling pathway

A New Hypoglycemic Prenylated Indole Alkaloid N-Oxide from Endophytic Fungus <i>Pallidocercospora crystalline</i>

Dihydrotrichodimerol Purified from the Marine Fungus<i> Acremonium</i><i> citrinum</i> Prevents NAFLD by Targeting PPAR?

Seco-polyprenylated acylphloroglucinols from Hypericum elodeoides induced cell cycle arrest and apoptosis in MCF-7 cells via oxidative DNA damage

Tautomeric phytosterols from Vernonia amygdalina Delile and their anti-cervical cancer activity

Polyhydric Stigmastane-Type Steroids Derivative from Vernonia amygdalina and Their Anti-Neuroinflammatory Activity

Bisabolane-type sesquiterpenes from <i>Vernonia amygdalina</i>: Absolute configuration and anti-inflammatory activity

Synthesis and Anti-Hepatoma Activities of U12 Derivatives Arresting G0/G1 Phase and Inducing Apoptosis by PI3K/AKT/mTOR Pathway

Phenolic glycosides and flavonoids with antioxidant and anticancer activities from Desmodium caudatum

Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance

Unprecedented Monoterpenoid Polyprenylated Acylphloroglucinols with a Rare 6/6/5/4 Tetracyclic Core, Enhanced MCF-7 Cells' Sensitivity to Camptothecin by Inhibiting the DNA Damage Response

Prenylated flavonoids from Ficus hirta induces HeLa cells apoptosis via MAPK and AKT signaling pathways

Jatrophane Diterpenoids from Euphorbia peplus as Multidrug Resistance Modulators with Inhibitory Effects on the ATR-Chk-1 Pathway

Lignans and phenylpropanoids from the roots of Ficus hirta and their cytotoxic activities

Cytotoxic polyprenylated phloroglucinol derivatives from Hypericum elodeoides Choisy modulating the transactivation of RXR alpha

Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ER alpha to inhibit RANKL signaling

Antiproliferative Sorbicillinoids From the Deep-Sea-Derived Penicillium allii-sativi

Cytotoxic compound triacremoniate from Marine Fungus Acremonium citrinum. MMF4

A new phenolic glycoside from Trollius chinensis Bunge with anti-inflammatory and antibacterial activities

Chemical Constituents from Endophytic Fungus Annulohypoxylon cf. stygium in Leaves of Anoectochilus roxburghii

12-Deacetyl-12-epi-Scalaradial, a Scalarane Sesterterpenoid from a Marine Sponge Hippospongia sp., Induces HeLa Cells Apoptosis via MAPK/ERK Pathway and Modulates Nuclear Receptor Nur77

POLYPHENOLS FROM Polygonum cuspidatum REACTIVATE LATENT HIV

Hyperelodiones A-C, monoterpenoid polyprenylated acylphoroglucinols from Hypericum elodeoides, induce cancer cells apoptosis by targeting RXR alpha

Andrastone A From the Deep-Sea-Derived Fungus Penicillium allii-sativi Acts as an Inducer of Caspase and RXR alpha-Dependent Apoptosis

Cytotoxic Components from Hypericum elodeoides Targeting RXR alpha and Inducing HeLa Cell Apoptosis through Caspase-8 Activation and PARP Cleavage

Steroids from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475 Induced Apoptosis via Retinoid X Receptor (RXR)-alpha Pathway

Stigmastane-type steroids with unique conjugated Delta(7,9(11)) diene and highly oxygenated side chains from the twigs of Vernonia amygdalina

Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice

Cytoskyrin C, an unusual asymmetric bisanthraquinone with cage-like skeleton from the endophytic fungus Diaporthe sp.

A New Xanthone from an Endophytic Fungus of Anoectochilus roxburghii

Polyphenols isolated from leaves of Vitis thunbergii var. taiwaniana regulate APP related pathway

Secondary metabolites of Xylaria sp., an endophytic fungus from Taxus mairei

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP

Cytotoxic metabolites from Botryotinia fuckeliana A-S-3: An endophytic fungus from Ajuga decumbens

Structure Elucidation and Biological Activity of Two New Trichothecenes from an Endophyte, Myrothecium roridum

Myrotheciumones: Bicyclic cytotoxic lactones isolated from an endophytic fungus of Ajuga decumbens

Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death

Structural modification of ginsenoside Rh-2 by fatty acid esterification and its detoxification property in antitumor

Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2

Three New Oblongolides from Phomopsis sp XZ-01, an Endophytic Fungus from Camptotheca acuminate

Advances in understanding the biosynthesis of fumonisins