已发表成果:
WOK 论文 52 篇;中文核心 34 篇;其它论文 11 篇;专利发明 16 个;
Unlocking the potential of bispecific ADCs for targeted cancer therapy
Stepping forward: T-cell redirecting bispecific antibodies in cancer therapy
A Dual-domain Engineered Antibody for Efficient HBV Suppression and Immune Responses Restoration
A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression <i>in vivo</i>
Anti-Epstein-Barr Virus BNLF2b for Mass Screening for Nasopharyngeal Cancer
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
Abnormally primed CD8 T cells: The Achilles' heel of CHB
Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail
Research progress and applications of nanobody in human infectious diseases
Development of functional antibodies against influenza B virus by activation-induced cytidine deaminase in hybridoma cells
Development of functional antibodies against influenza B virus by activation-induced cytidine deaminase in hybridoma cells
Recent progress in antibody-based therapeutics for triple-negative breast cancer
Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and synergizes with CTLA-4 or TIM-3 blockade
HER2/PD1 bispecific antibody in IgG4 subclass with superior anti-tumour activities
A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy
A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating
Comparison of Seven Commercial Severe Acute Respiratory Syndrome Coronavirus 2 Nucleic Acid Detection Reagents with Pseudovirus as Quality Control Material
Quantitative evaluation of protective antibody response induced by hepatitis E vaccine in humans
Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development
EGFR-targeted CAR-T cells are potent and specific in suppressing triple-negative breast cancer both in vitro and in vivo
COVID-19: Progress in diagnostics, therapy and vaccination
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency
Vesicular Antibodies: A Bioactive Multifunctional Combination Platform for Targeted Therapeutic Delivery and Cancer Immunotherapy
Epitope clustering analysis for vaccine-induced human antibodies in relationship to a panel of murine monoclonal antibodies against HPV16 viral capsid
Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR
Efficient development of a stable cell pool for antibody production using a single plasmid
A novel therapeutic anti-HBV antibody with increased binding to human FcRn improves in vivo PK in mice and monkeys
Molecular and functional analysis of monoclonal antibodies in support of biologics development
A bispecific broadly neutralizing antibody against enterovirus 71 and coxsackievirus A16 with therapeutic potential
A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses
Active evolution of memory B-cells specific to viral gH/gL/pUL128/130/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection
Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen
A human monoclonal antibody against HPV16 recognizes an immunodominant and neutralizing epitope partially overlapping with that of H16.V5
In vitro affinity maturation and characterization of anti-P24 antibody for HIV diagnostic assay
Developing a genetically encoded green fluorescent protein mutant for sensitive light-up fluorescent sensing and cellular imaging of Hg(II)
Maximizing antibody production in suspension-cultured mammalian cells by the customized transient gene expression method
Mimotope ELISA for Detection of Broad Spectrum Antibody against Avian H5N1 Influenza Virus
Induction of cross-reactive antibodies against mimotopes of H5N1 hemagglutinin
Humanized antibodies with broad-spectrum neutralization to avian influenza virus H5N1
Peptide mimics of a conserved H5N1 avian influenza virus neutralization site
Construction and characterization of the chimeric antibody 8C11 to the hepatitis E virus
Variants of green fluorescent protein GFPxm
Bioluminescence of Aequorea macrodactyla, a common jellyfish species in the East China Sea
抗体靶向的免疫激动性药物在肿瘤免疫治疗中的研究进展
中国生物工程杂志,1671-8135,2024-06-25.三特异性抗体在肿瘤免疫治疗中的研究进展
生命科学,1004-0374,2024-04-02.纳米抗体在自身免疫性疾病中的应用
中国免疫学杂志,1000-484X,2024-01-20.T细胞重定向双特异性抗体在肿瘤治疗中的挑战与应对策略
中国生物工程杂志,1671-8135,2023-06-25.抗病毒抗体Fc效应功能研究进展
病毒学报,1000-8721,2023-05-09.CAR-T联合疗法治疗实体瘤的研究进展
中国生物工程杂志,1671-8135,2022-12-25.ADC药物的抗体组成及其作用靶点研究进展
中国生物工程杂志,1671-8135,2022-05-25.免疫检查点抑制剂在慢性乙型肝炎中的研究进展
微生物学报,0001-6209,2021-01-28.纳米抗体在传染病的预防、诊断和治疗中的应用
中国生物工程杂志,1671-8135,2020-10-15.抗GPC3单链抗体的制备及其在肝细胞癌靶向检测中的应用
生物工程学报,1000-3061,2020-08-13.新型冠状病毒肺炎的治疗药物及疫苗研究进展
厦门大学学报(自然科学版),0438-0479,2020-04-02.紧密连接蛋白claudins应用于肿瘤治疗的进展
生物工程学报,1000-3061,2019-06-25.CHO细胞工程化改造的研究进展
生物技术,1004-311X,2019-06-20.再循环抗体的研究进展
生物工程学报,1000-3061,2019-02-25.基因编辑技术
中国生物化学与分子生物学报,1007-7626,2018.抗体应答研究技术在非人灵长类感染与免疫模型中的应用
病毒学报,1000-8721,2018.治疗性抗体半衰期改造研究进展
中国生物工程杂志,1671-8135,2017.一株乙型肝炎病毒鼠单抗的人源化及生物学活性鉴定
厦门大学学报(自然科学版),0438-0479,2016-05-16.抗H5亚型禽流感病毒单链抗体在毕赤酵母中的分泌型表达和生物活性分析
病毒学报,1000-8721,2011.绿色荧光蛋白——发现、表达和发展
生物物理学报,1000-6737,2008-12-15.高致病性禽流感病毒血凝素蛋白广谱中和表位模拟肽的筛选与鉴定
病毒学报,1000-8721,2008-11-15.分子对接预测H5亚型禽流感病毒的广谱中和表位
科学通报,0023-074X,2008-01-30.高致病性禽流感病毒H5N1中和抗体的单链抗体构建与活性鉴定
生物工程学报,1000-3061,2007-03-30.H5N1禽流感病毒血凝素抗原快速检测试剂对不同现场标本的检测比较
病毒学报,1000-8721,2007-03-30.一种新型H5N1禽流感病毒血凝素抗原快速检测试剂的建立
病毒学报,1000-8721,2006-11-30.亲和层析法用于噬菌体抗体库的筛选
病毒学报,1000-8721,2006-01-30.SARS冠状病毒核衣壳(N)蛋白不同区域的原核表达
病毒学报,1000-8721,2005-03-20.抗HEV嵌合抗体的构建及在CHO细胞中的表达
病毒学报,1000-8721,2004-12-30.乙型肝炎病毒pre-S1区中和抗体可变区的原核表达
生物工程学报,1000-3061,2004-11-23.二种多管水母光蛋白基因的分离、表达及生物活性初步研究
海洋学报(中文版),0253-4193,2004-07-13.重组人类T淋巴细胞白血病病毒抗原及双抗原夹心法ELISA抗体诊断试剂盒的研制
病毒学报,1000-8721,2004-06-30.应用噬菌体随机肽库技术筛选戊型肝炎病毒中和表位模拟肽
生物工程学报,1000-3061,2003-11-23.一种高效、稳定的分泌型原核表达载体的构建及应用
厦门大学学报(自然科学版),0438-0479,2003-07-30.橙色荧光蛋白——绿色荧光蛋白GFPxm的改造
生物工程学报,1000-3061,2003-01-23.白细胞介素12在实体瘤治疗中的研究进展
肿瘤研究与临床,1006-9801,2022-08-28.新型冠状病毒核酸血液筛查系统的检测性能评价
国际病毒学杂志,1673-4092,2020-12-25.双特异性抗体在肿瘤治疗中的研究进展
肿瘤研究与临床,1006-9801,2018.稳定表达可视化hFcRn的MDCK细胞株构建
生物技术,1004-311X,2017.表位疫苗研究进展
中国生物工程杂志,1671-8135,2007-11-15.建构主义知识观对教学的影响
唐山学院学报,1672-349X,2007-07-15.多样性人源天然噬菌体抗体库的构建及初步应用
细胞与分子免疫学杂志,1007-8738,2006-11-18.噬菌体抗体库固相筛选条件的初步研究
细胞与分子免疫学杂志,1007-8738,2006-09-18.抗HEV中和抗体13D8的单链抗体的构建及表达
细胞与分子免疫学杂志,1007-8738,2004-10-30.抗HBV中和抗体MA18/7轻链可变区V_L与GFP融合蛋白的表达及生物活性测定
细胞与分子免疫学杂志,1007-8738,2004-08-30.一种高效、稳定的分泌型原核表达载体的构建及应用
生物技术通讯,1009-0002,2003-12-30.H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
CN103254308B,2015-01-21.特异性结合H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
CN101607995B,2013-05-01.一种H5亚型禽流感病毒血凝素蛋白的单克隆抗体,其制备方法及其用途
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