Maternal <i>Ezh1/2</i> deficiency impairs the function of mitochondria in mouse oocytes and early embryos

Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution

Progesterone and cAMP synergistically induce SHP2 expression via PGR and CREB1 during uterine stromal decidualization

miR-9 and miR-181a Target Gab2 to Inhibit the Proliferation and Migration of Hepatocellular Carcinoma HepG2 Cells

Tyrosine phosphatase SHP2 in ovarian granulosa cells balances follicular development by inhibiting PI3K/AKT signaling

P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation

Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse

Liver-specific overexpression of Gab2 accelerates hepatocellular carcinoma progression by activating immunosuppression of myeloid-derived suppressor cells

Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling

FOXD3 and GAB2 as a pair of rivals antagonistically control hepatocellular carcinogenesis

Biallelic mutations in spermatogenesis and centriole-associated 1 like (SPATC1L) cause acephalic spermatozoa syndrome and male infertility

Shp2 in uterine stromal cells critically regulates on time embryo implantation and stromal decidualization by multiple pathways during early pregnancy

A Novel Meiosis-Related lncRNA, Rbakdn, Contributes to Spermatogenesis by Stabilizing Ptbp2

Bi-allelic mutations in DNAH7 cause asthenozoospermia by impairing the integrality of axoneme structure

Biallelic mutations in KATNAL2 cause male infertility due to oligo-astheno-teratozoospermia

Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice

Mutations in ZP4 are associated with abnormal zona pellucida and female infertility

Identification of a novel deletion mutation in DPY19L2 from an infertile patient with globozoospermia: a case report

The role of tyrosine phosphatase Shp2 in spermatogonial differentiation and spermatocyte meiosis

Loss-of-function mutations in SPEF2 cause multiple morphological abnormalities of the sperm flagella (MMAF)

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia

DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella

Magnesium-dependent Phosphatase (MDP) 1 is a Potential Suppressor of Gastric Cancer

Nuclear Shp2 directs normal embryo implantation via facilitating the ERa tyrosine phosphorylation by the Src kinase

Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice

Integrated miRNA and mRNA expression profiling to identify mRNA targets of dysregulated miRNAs in non-obstructive azoospermia

A Prognosis Classifier for Breast Cancer Based on Conserved Gene Regulation between Mammary Gland Development and Tumorigenesis: A Multiscale Statistical Model

Identification, Characterization and Application of a G-Quadruplex Structured DNA Aptamer against Cancer Biomarker Protein Anterior Gradient Homolog 2

Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2

A G-Quadruplex Aptamer Inhibits the Phosphatase Activity of Oncogenic Protein Shp2 in vitro

A novel screening model for the molecular drug for diabetes and obesity based on tyrosine phosphatase Shp2

Repression of Lim only protein 4-activated transcription inhibits proliferation and induces apoptosis of normal mammary epithelial cells and breast cancer cells