A comprehensive study on solvent effect and establishment of n-hexane solvent system based normal-phase liquid chromatography x reversed-phase liquid chromatography for isolation of natural products

Hinokione: an abietene diterpene with pancreatic β cells regeneration and hypoglycemic activity, and other derivatives with novel structures from the woods of <i>Agathis dammara</i>

Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma

Design, synthesis, and biological evaluation of novel 4,4′-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer

Discovery of 5-(Pyrimidin-2-ylamino)-1<i>H</i>-indole-2-carboxamide Derivatives as Nur77 Modulators with Selective and Potent Activity Against Triple-Negative Breast Cancer

Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice

Discovery of bipyridine amide derivatives targeting pRXR?-PLK1 interaction for anticancer therapy

Development of an On-Line Two-dimensional Normal Phase Liquid Chromatography System for Analysis of Weakly Polar Samples

Design and synthesis of N-(1-(6-(substituted phenyl)-pyridazin-3-yl)-piperidine-3-yl)-amine derivatives as JMJD6 inhibitors

Effects of Sophora flavescens aiton and the absorbed bioactive metabolite matrine individually and in combination with 5-fluorouracil on proliferation and apoptosis of gastric cancer cells in nude mice

Inonotus obliquus and its bioactive compounds alleviate non-alcoholic fatty liver disease via regulating FXR/SHP/SREBP-1c axis

Three new compounds from Anoectochilus roxburghii (Wall.) Lindl

Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma

Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo

Anti-inflammatory sesquiterpenoids from the heartwood of Juniperus formosana Hayata

New Sorbicillinoids with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus Hypocrea jecorina H8

Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish

Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activityin vitroandin silico

Two new troponoides with anti-inflammatory activity from the stems of Juniperus formosana Hayata

The Protective Effects of Zornia diphylla (L.) Pers. Against Acute Liver Injury Induced by Carbon Tetrachloride in Mice

New cyclopentenoneacrylic acid derivatives from a marine-derived fungus Trichoderma atroviride H548

Discovery of new chalone adamantyl arotinoids having RXR alpha-modulating and anticancer activities

Two new compounds from a mangrove sediment-derived fungus Penicillium polonicum H175

Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome

Glycine metabolomic changes induced by anticancer agents in A549 cells

Fungal diversity of deep-sea sediments in Mid-Oceanic Ridge area of the East Pacific and the South Indian Oceans

Synthesis and biological evaluations of N '-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents

A self-attention based message passing neural network for predicting molecular lipophilicity and aqueous solubility

Two novel species of the family Bacillaceae: Oceanobacillus piezotolerans sp. nov. and Bacillus piezotolerans sp. nov., from deep-sea sediment samples of Yap Trench

Two New Cytotoxic Compounds from a Deep-Sea Penicillum citreonigrum XT20-134

Isolation and characterization of a novel piezotolerant bacterium Lysinibacillus yapensis sp. nov., from deep-sea sediment of the Yap Trench, Pacific Ocean

New beta-Lactone with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived Fungus MCCC3A00957

Gradual Gradient Two-Dimensional Preparative Liquid Chromatography System for Preparative Separation of Complex Natural Products

The Protective Effects of Ciji-Hua'ai-Baosheng II Formula on Chemotherapy-Treated H-22 Hepatocellular Carcinoma Mouse Model by Promoting Tumor Apoptosis

Safety Evaluation of a New Traditional Chinese Medical Formula, Ciji-Hua'ai-Baosheng II Formula, in Adult Rodent Models

Insights into the stereoselectivity of human SETD7 methyltransferase

Chromones and tannins from the fruit of Euscaphis japonica var. wupingensis

New Bis-Alkenoic Acid Derivatives from a Marine-Derived Fungus Fusarium solani H915

Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Aspergillus terreus Y10

Effective natural antifouling compounds from the plant Nerium oleander and testing

Two new cytochalasan derivatives from Chaetomium globosum SNSHI-5, a fungus derived from extreme environment

The effect of V155M mutation on the complex of hSTING and 2'3'-cGAMP: an in silico study case

Development of an on-line mixed-mode gel liquid chromatography×reversed phase liquid chromatography method for separation of water extract from Flos Carthami

Macrolactins from Marine-Derived Bacillus subtilis B5 Bacteria as Inhibitors of Inducible Nitric Oxide and Cytokines Expression

Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents

Comprehensive two-dimensional normal-phase liquid chromatography × reversed-phase liquid chromatography for analysis of toad skin

New on-line separation workflow of microbial metabolites via hyphenation of analytical and preparative comprehensive two-dimensional liquid chromatography

PHB-Based Gels as Delivery Agents of Chemotherapeutics for the Effective Shrinkage of Tumors

Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library

On-line comprehensive two-dimensional normal-phase liquid chromatography×reversed-phase liquid chromatography for preparative isolation of toad venom

Supramolecular cyclodextrin nanocarriers for chemo- and gene therapy towards the effective treatment of drug resistant cancers

A new macrolactin antibiotic from deep sea-derived bacteria Bacillus subtilis B5

PLA-based thermogel for the sustained delivery of chemotherapeutics in a mouse model of hepatocellular carcinoma

On-line two-dimensional countercurrent chromatography × high performance liquid chromatography system with a novel fragmentary dilution and turbulent mixing interface for preparation of coumarins from Cnidium monnieri

Online polar two phase countercurrent chromatographyhigh performance liquid chromatography for preparative isolation of polar polyphenols from tea extract in a single step

On-line comprehensive two-dimensional normal-phase liquid chromatographyreversed-phase liquid chromatography for preparative isolation of Peucedanum praeruptorum

Two-dimensional countercurrent chromatography×high performance liquid chromatography with heart-cutting and stop-and-go techniques for preparative isolation of coumarin derivatives from Peucedanum praeruptorum Dunn

Two-dimensional preparative liquid chromatography system for preparative separation of minor amount components from complicated natural products

Two New Cytotoxic Indole Alkaloids from a Deep-Sea Sediment Derived Metagenomic Clone

Two-dimensional countercurrent chromatography x high performance liquid chromatography for preparative isolation of toad venom

Differential proteomic analysis of HL60 cells treated with secalonic acid F reveals caspase 3-induced cleavage of Rho GDP dissociation inhibitor 2

Inhibition of beta-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

Two new compounds from marine-derived fungus Penicillium sp F11

Prediagnostic methods for the hemolysis of herbal medicine injection

A novel indole alkaloid from deep-sea sediment metagenomic clone-derived Escherichia coli fermentation broth

DNA damage induced by shikonin in the presence of Cu(II) ions: potential mechanism of its activity to apoptotic cell death

Cytotoxic constituents from the skin of the toad Bufo bufo gargarizans

Studies on cytotoxic constituents from the skin of the toad Bufo bufo gargarizans

Dammarane-type saponins from Panax quinquefolium and their inhibition activity on human breast cancer MCF-7 cells

Structure elucidation and complete NMR spectral assignments of four new diterpenoids from Smallantus sonchifolius

Structure elucidation and complete NMR spectral assignments of two new dammarane-type tetraglycosides from Panax quinquefolium

Three novel compounds from the leaves of Smallanthus sonchifolius