Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration

SHP-1 Regulates CD8+T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay

Themis suppresses the effector function of CD8<SUP>+</SUP> T cells in acute viral infection

Post-translational Modifications of RhoB in Cell Fate Determination

TMEM25 inhibits monomeric EGFR-mediated STAT3 activation in basal state to suppress triple-negative breast cancer progression

Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system

Themis is indispensable for IL-2 and IL-15 signaling in T cells

Investigation of Effects of the Spectral Library on Analysis of diaPASEF Data

The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity

Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer

CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis

Smurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP-1c in an E3 activity-independent manner

Monoubiquitination of p120-catenin is essential for TGF beta-induced epithelial-mesenchymal transition and tumor metastasis

SMURF1 aggravates liver steatosis by stabilizing SREBP-1C in an E3 catalytic activity independent manner

A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases

DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane

ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage

Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

IL-36 gamma Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses

The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis

Impeded Nedd4-1-Mediated Ras Degradation Underlies Ras-Driven Tumorigenesis

PKA/Smurf1 signaling-mediated stabilization of Nur77 is required for anticancer drug cisplatin-induced apoptosis

T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells

Ubiquitination in Rho Signaling

Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity

Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP)