Discovery of 5-(Pyrimidin-2-ylamino)-1<i>H</i>-indole-2-carboxamide Derivatives as Nur77 Modulators with Selective and Potent Activity Against Triple-Negative Breast Cancer

Knockout of Nur77 Leads to Amino Acid, Lipid, and Glucose Metabolism Disorders in Zebrafish

Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo

Impact of macroporous silica nanoparticles at sub-50nm on bio-behaviors and biosafety in drug-resistant cancer models

"One stone, two birds": engineering 2-D ultrathin heterostructure nanosheet BiNS@NaLnF(4) for dual-modal computed tomography/magnetic resonance imaging guided, photonic synergetic theranostics

Centrosomal Localization of RXR alpha Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability

Synthesis and discovery of omega-3 polyunsaturated fatty acid- alkanolamine (PUFA-AA) derivatives as anti-inflammatory agents targeting Nur77

Alisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signaling-initiated G(1) cell cycle arrest and apoptosis: A quantitative proteomic study

Recent Progress in Macromolecule-Anchored Hybrid Gold Nanomaterials for Biomedical Applications

Celastrol binds to its target protein via specific noncovalent interactions and reversible covalent bonds

A New Approach to Synthesize of 4-Phenacylideneflavene Derivatives and to Evaluate Their Cytotoxic Effects on HepG2 Cell Line

A phenylacetaldehyde-flavonoid adduct, 8-C-(E-phenylethenyl)-norartocarpetin, exhibits intrinsic apoptosis and MAPK pathways-related anticancer potential on HepG2, SMMC-7721 and QGY-7703

TBMS1 exerts its cytotoxicity in NCI-H460 lung cancer cells through nucleolar stress-induced p53/MDM2-dependent mechanism, a quantitative proteomics study

Honokiol sensitizes breast cancer cells to TNF-alpha induction of apoptosis by inhibiting Nur77 expression

Nitrostyrene Derivatives Act as RXR alpha Ligands to Inhibit TNF alpha Activation of NF-kappa B

Characterization of Antiproliferative Activity Constituents from Artocarpus heterophyllus

Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death

Multiple pathways were involved in tubeimoside-1-induced cytotoxicity of HeLa cells