Ozone exposure affects corneal epithelial fate by promoting mtDNA leakage and cGAS/STING activation

Corneal stromal filler injection of gelatin-based photocurable hydrogels for maintaining the corneal thickness and reconstruction of corneal stroma

Clickable corneal neovascularization therapy with ROS-responsive polydopamine silica nanoparticles loaded with fenofibrate

Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction

Effective Corneal Neovascularization Therapy with Ros-Responsive Polydopamine Silica Nanoparticles Loaded with Fenofibrate

Quantitative Proteomics of the CDK9 Interactome Reveals a Function of the HSP90-CDC37-P-TEFb Complex for BETi-Induced HIV-1 Latency Reactivation

Isobaric Stable Isotope N-Phosphorylation Labeling (iSIPL) for Ultrasensitive Proteome Quantification

Isobaric Stable Isotope N-Phosphorylation Labeling (iSIPL) for Ultrasensitive Proteome Quantification

The synthesis of PROTAC molecule and new target KAT6A identification of CDK9 inhibitor iCDK9

Decellularized squid mantle scaffolds as tissue-engineered corneal stroma for promoting corneal regeneration

Receptor-binding domain-anchored peptides block binding of severe acute respiratory syndrome coronavirus 2 spike proteins with cell surface angiotensin-converting enzyme 2

Phenotypic and Transcriptomics Analyses Reveal Underlying Mechanisms in a Mouse Model of Corneal Bee Sting

Polystyrene microplastic particles: In vivo and in vitro ocular surface toxicity assessment

Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage

Polyphenol Extracts from Grape Seeds and Apple Can Reactivate Latent HIV-1 Transcription through Promoting P-TEFb Release from 7SK snRNP

A natural product targets BRD4 to inhibit phase separation and gene transcription

Phenotypic and transcriptomic changes in the corneal epithelium following exposure to cigarette smoke

Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure

Real-time confocal microscopy imaging of corneal cytoarchitectural changes induced by different stresses

Novel Cell Culture Paradigm Prolongs Mouse Corneal Epithelial Cell Proliferative Activity in vitro and in vivo

Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent

Resveratrol Promotes HIV-1 Tat Accumulation via AKT/FOXO1 Signal-ing Axis and Potentiates Vorinostat to Antagonize HIV-1 Latency

Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors

ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation

Synthesis and biological evaluations of N '-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents

POLYPHENOLS FROM Polygonum cuspidatum REACTIVATE LATENT HIV

Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription

JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes

Onion Epithelial Membrane Scaffolds Transfer Corneal Epithelial Layers in Reconstruction Surgery

The role of autophagy in the pathogenesis of exposure keratitis

A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis

Epithelial dysplasia in pterygium postoperative granuloma

Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1

A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter

Stable isotope N-phosphoryl amino acids labeling for quantitative profiling of amine-containing metabolites using liquid chromatography mass spectrometry

Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells

Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNP

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription

Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism

Mechanism and factors that control HIV-1 transcription and latency activation

Fibrin glue-assisted for the treatment of corneal perforations using glycerin-cryopreserved corneal tissue

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

Viral-host interactions that control HIV-1 transcriptional elongation

Hypoxia affects in vitro proliferation and differentiation of mouse corneal epithelial progenitor cell

Mutual information analysis reveals coevolving residues in Tat that compensate for two distinct functions in HIV-1 gene expression