已发表成果:
WOK 论文 49 篇;中文核心 6 篇;其它论文 1 篇;
TCR-like bispecific antibodies toward eliminating infected hepatocytes in HBV mouse models
Orchestrated Codelivery of Peptide Antigen and Adjuvant to Antigen-Presenting Cells by Using an Engineered Chimeric Peptide Enhances Antitumor T-Cell Immunity
Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels
Swine pseudorabies virus attenuated vaccine reprograms the kidney cancer tumor microenvironment and synergizes with PD-1 blockade
A Dual-domain Engineered Antibody for Efficient HBV Suppression and Immune Responses Restoration
Micronanoparticled risedronate exhibits potent vaccine adjuvant effects
A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression <i>in vivo</i>
Safety and efficacy of the intranasal spray SARS-CoV-2 vaccine dNS1-RBD: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
MHC class II regulation of CD8+T cell tolerance and implications in autoimmunity and cancer immunotherapy
The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters
Combination therapy of therapeutic antibody and vaccine or entecavir in HBV carrier mice
A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19
Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine
New discovery of high-affinity SARS-CoV-2 spike S2 protein binding peptide selected by PhIP-Seq
Potential of conserved antigenic sites in development of universal SARS-like coronavirus vaccines
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2
Safety and immunogenicity of a live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine in adults: randomised, double-blind, placebo-controlled, phase 1 and 2 trials
Pre-Clinical Development of a Potent Neutralizing Antibody MW3321 With Extensive SARS-CoV-2 Variants Coverage
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
Cross-species tropism and antigenic landscapes of SARS-CoV-2 variants
A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy
A review of the safety and efficacy of current COVID-19 vaccines
Azacytidine targeting SARS-CoV-2 viral RNA as a potential treatment for COVID-19
A cell-penetrating whole molecule antibody targeting intracellular HBx suppresses hepatitis B virus via TRIM21-dependent pathway (vol 8, pg 549, 2018)
A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters
Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster
Several FDA-Approved Drugs Effectively Inhibit SARS-CoV-2 Infection in vitro
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors
Preparation and functional evaluation of monoclonal antibodies targeting Hepatitis B Virus Polymerase
Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection
Inflammation-related adverse reactions following vaccination potentially indicate a stronger immune response
Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 2019
A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice
Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates
Robust neutralization assay based on SARS-CoV-2 S-protein-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressing BHK21 cells
Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection
HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation
Role of quantitative hepatitis B core antibody levels in predicting significant liver inflammation in chronic hepatitis B patients with normal or near-normal alanine aminotransferase levels
The unique antibody suppresses HBV viremia and reduces hepatocarcinogenesis in HBV-transgenic mice
A cell-penetrating whole molecule antibody targeting intracellular HBx suppresses hepatitis B virus via TRIM21-dependent pathway
The gRNA-miRNA-gRNA Ternary Cassette Combining CRISPR/Cas9 with RNAi Approach Strongly Inhibits Hepatitis B Virus Replication
RNA与重大疾病诊疗
科学通报,0023-074X,2024-08-29.水泡性口炎病毒作为疫苗载体的应用
病毒学报,1000-8721,2023-06-26.面向新冠肺炎疫情防控需求的应用基础研究
中国科学基金,1000-8217,2022-08-30.新冠疫苗点亮希望之光
中国科学基金,1000-8217,2021-04-25.疫苗免疫原的研究进展和趋势
中国科学基金,1000-8217,2020-10-25.抗PD-L1单抗的研制及其对乙型肝炎病毒的抑制效果初步研究
中国免疫学杂志,1000-484X,2016-07-20.治疗性抗乙型肝炎表面抗原单克隆抗体的研究进展
中华微生物学和免疫学杂志,,2021-10-31.