已发表成果:
WOK 论文 72 篇;中文核心 7 篇;专利发明 2 个;
Structural insights into activation mechanisms on NADase of the bacterial DSR2 anti-phage defense system
A cryptic site in class 5 epitope of SARS-CoV-2 RBD maintains highly conservation across natural isolates
Major HBV splice variant encoding a novel protein important for infection
Risedronate-functionalized manganese-hydroxyapatite amorphous particles: A potent adjuvant for subunit vaccines and cancer immunotherapy
Rational design of a cross-type HPV vaccine through immunodominance shift guided by a cross-neutralizing antibody
Neutralizing antibodies against EBV gp42 show potent <i>in vivo</i> protection and define novel epitopes
Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection
Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant
Targeting herpesvirus entry complex and fusogen glycoproteins with prophylactic and therapeutic agents
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
Risedronate-Functionalized Manganese-Calcium Phosphate Nanoparticles: A Potent Adjuvant for Subunit Vaccines and Cancer Immunotherapy
Structure and proposed DNA delivery mechanism of a marine roseophage
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16
Truncated glycoprotein E of varicella-zoster virus is an ideal immunogen for <i>Escherichia coli</i>-based vaccine design
Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine
Editorial: Antiviral drugs and vaccines against important human respiratory viruses
Omics-guided bacterial engineering of Escherichia coli ER2566 for recombinant protein expression
Characterization of an Escherichia coli-derived triple-type chimeric vaccine against human papillomavirus types 39, 68 and 70
A bacterially expressed triple-type chimeric vaccine against human papillomavirus types 51, 69, and 26
A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode
Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail
Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses
Endodomain truncation of the HIV-1 envelope protein improves the packaging efficiency of pseudoviruses
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2
Protective anti-gB neutralizing antibodies targeting two vulnerable sites for EBV-cell membrane fusion
Baculovirus Display of Varicella-Zoster Virus Glycoprotein E Induces Robust Humoral and Cellular Immune Responses in Mice
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron
A Neutralizing Antibody Targeting gH Provides Potent Protection against EBV Challenge In Vivo
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice
Structures of pseudorabies virus capsids
Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209
A stepwise docking molecular dynamics approach for simulating antibody recognition with substantial conformational changes
Unsupervised Cryo-EM Images Denoising and Clustering Based on Deep Convolutional Autoencoder and K-Means plus
Engineering for an HPV 9-valent vaccine candidate using genomic constitutive over-expression and low lipopolysaccharide levels in Escherichia coli cells
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters
A Novel Clustering Method Using Variational Autoencoder with Reliable Sample Decision and Balanced K-Means++ for Single-particle Cryo-EM Images
Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating
Rapid Development of SARS-CoV-2 Spike Protein Receptor-Binding Domain Self-Assembled Nanoparticle Vaccine Candidates
Virus-Free and Live-Cell Visualizing SARS-CoV-2 Cell Entry for Studies of Neutralizing Antibodies and Compound Inhibitors
Immunization with a Self-Assembled Nanoparticle Vaccine Elicits Potent Neutralizing Antibody Responses against EBV Infection
Machine Learning for Structure Determination in Single-Particle Cryo-Electron Microscopy: A Systematic Review
Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids
Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs
Genome re-sequencing and reannotation of the Escherichia coli ER2566 strain and transcriptome sequencing under overexpression conditions
Rational design of a multi-valent human papillomavirus vaccine by capsomere-hybrid co-assembly of virus-like particles
Recent Progress on the Versatility of Virus-Like Particles
Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16
A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates
Viral neutralization by antibody-imposed physical disruption
Altered antigenicity and immunogenicity of human papillomavirus virus-like particles in the presence of thimerosal
Construction of a bacterial surface display system based on outer membrane protein F
Hepatitis E vaccine candidate harboring a non-particulate immunogen of E2 fused with CRM197 fragment A
Characterization of native-like HIV-1 gp140 glycoprotein expressed in insect cells
An HRP-labeled lateral flow immunoassay for rapid simultaneous detection and differentiation of influenza A and B viruses
Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection
Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency
Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
T=4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display
N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro
Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10
Identification of Strategic Residues at the Interface of Antigen-Antibody Interactions by In Silico Mutagenesis
A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses
Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
A novel inactivated enterovirus 71 vaccine can elicit cross-protective immunity against coxsackievirus A16 in mice
A shared N-terminal hydrophobic tail for the formation of nanoparticulates
The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction
Virus-mimetic nanovesicles as a versatile antigen-delivery system
EB病毒糖蛋白中和抗体研究进展
中国科学:生命科学,1674-7232,2024-12-11.EB病毒结构研究进展
中国科学:生命科学,1674-7232,2024-12-10.基于对比学习的冷冻电镜单颗粒图像聚类算法
厦门大学学报(自然科学版),0438-0479,2022-11-28.厦门市健康人群肠道病毒D68型血清流行病学调查
病毒学报,1000-8721,2021-07-23.肠道病毒68型新型中和试验方法的建立及其初步应用
病毒学报,1000-8721,2017.悬浮驯化HEK-293FT细胞表达人乳头瘤病毒16型假病毒及其冷冻电镜结构解析
病毒学报,1000-8721,2016-09-15.杆状病毒-昆虫细胞系统表达的戊型肝炎病毒衣壳蛋白p495的纯化、结构解析以及免疫原性分析
病毒学报,1000-8721,2016-05-15.